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Usage

Uses

Used in Organic Synthesis:
2-AMINO-1-(2,5-DIMETHOXYPHENYL)-1-PROPANONE is used as a building block in organic synthesis for the creation of various complex organic compounds. Its unique structure allows for the formation of new compounds with different properties, expanding the scope of chemical research and development.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-AMINO-1-(2,5-DIMETHOXYPHENYL)-1-PROPANONE serves as a key component in the development of new drugs and pharmaceuticals. Its versatile chemical properties enable the synthesis of novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used as a Reagent in Chemical Reactions:
2-AMINO-1-(2,5-DIMETHOXYPHENYL)-1-PROPANONE is utilized as a reagent in various chemical reactions to form new compounds with distinct properties and applications. Its ability to participate in a wide range of reactions makes it an indispensable tool in the field of chemistry, facilitating the discovery and synthesis of innovative materials and substances.

Upstream product

• 121347-31-7 1-(2,5-dimethoxyphenyl)-2-hydroxyimino-1-acetone 
• 5803-30-5 2',5'-dimethoxypropiophenone 
• 742095-47-2 (RS)-2-trifluoroacetamido-1-(2,5-dimethoxyphenyl)-1-propanone 

Downstream Products

• 390-28-3 2-amino-1-(2,5-dimethoxyphenyl)-1-propanol 

Relevant academic research and scientific papers

A salt structure the armor oxygen is bright erythro method for the preparation of acid

A disclosed preparation method for erythro-structure methoxamine hydrochloride comprises the following steps: (1) dissolving an initial raw material 2,5-dimethylpropiophenone in an organic solvent, under the condition of introducing dry hydrogen chloride gas, dropwise adding a 1-butyl nitrite solution to perform an oximation reaction, so as to obtain an intermediate I; (2) under the acidic condition, taking a methanol solution as a solvent, take palladium on activated carbon as a catalyst, employing hydrogen to reduce the oximido group in the intermediate I, so as to obtain an intermediate II; and (3) performing hydrogenation reduction reaction on the intermediate II to obtain the erythro-structure methoxamine hydrochloride. The method provided by the invention is simple in operation, economic, environment-friendly, mild in reaction conditions, excellent in product quality and high in yield, and can help to obtain the single erythro-structure methoxamine hydrochloride.

MAO inhibition by arylisopropylamines: The effect of oxygen substituents at the β-position

Twenty-nine arylisopropylamines, substituted at the β-position of their side chain by an oxo, hydroxy, or methoxy group, were evaluated in vitro as MAO-A and MAO-B inhibitors. The oxo derivatives ('cathinones') were in general less active as MAO-A inhibitors than the corresponding arylisopropylamines, but exhibited an interesting MAO-B inhibiting activity, which was absent in the hydroxy, methoxy, and β-unsubstituted analogues. These results suggest that selective affinity for the two MAO isoforms in this family of compounds is modulated not only by the aryl substitution pattern but also by the side-chain substituents on the arylalkylamine scaffold.