103593-79-9

Usage

Molecular structure

1H-Pyrazole-4-carboxaldehyde, 3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenylconsists of a pyrazole ring with a carboxaldehyde functional group and a phenyl group attached, as well as a benzopyran ring system and a ketone functional group.

Potential applications

1H-Pyrazole-4-carboxaldehyde, 3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl- may have potential applications in chemical synthesis, pharmaceuticals, and materials science due to its unique structure and reactivity.

Need for further research

Further research is needed to fully understand the properties and potential uses of 1H-Pyrazole-4-carboxaldehyde, 3-(2-oxo-2H-1-benzopyran-3-yl)-1-phenyl-.

Upstream product

• 103593-74-4 3-{1-[(E)-2-phenylhydrazono]ethyl}-2H-chromen-2-one 
• 68-12-2 N,N-dimethyl-formamide 
• 90-02-8 salicylaldehyde 
• 103593-74-4 3-(1-(2-phenylhydrazono)ethyl)-2H-chromen-2-one 
• 100-63-0 phenylhydrazine 
• 3949-36-8 3-acetylcoumarin 

Downstream Products

• 372098-62-9 5-((3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 423155-28-6 dihydro-5-((3-(2-oxo-2H-chromene-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxopyrimidine-4,6(1H,5H)-dione 

Relevant academic research and scientific papers

Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors

Two series, coumarin-linked to thiazolidinone via a pyrazole linker (6a-m, Series 1) and coumarin-linked 1,2,3-triazoles (5a-j, Series 2) were synthesized and the synthesized compounds were subjected for evaluation against the four physiologically and pha

Synthesis of some hippuric acid substrate linked novel pyrazoles as antimicrobial agents

Escalating resistance of microorganisms to the currently accessible antimicrobial drugs has forced to synthesize some novel biologically active compounds as efficient alternates via economical substrates. Hence, hippuric acid was used as one of the starting materials to synthesize pyrazole derivatives. All the synthesized compounds were characterized by IR, NMR (1H & 13C) and mass spectral data. The antimicrobial potential of synthesized compounds has been explored against four bacterial and two fungal strains. Among the 12 compounds, 3 compounds 8j, 8k and 8l were found to exhibit prominent antimicrobial potential as compared with the standards ciprofloxacin and amphotericin-B.

Synthesis of novel substituted 3-(4-((1H-benzo[d]imidazol-2-ylthio)methyl)-1-phenyl-1H-pyrazol-3-yl)-2H-chromen-2-ones: various approaches

Abstract: Considering benzimidazole as a privileged structure for developing probes of impressive pharmacological potentials, some new coumarin and pyrazole conjugates of benzimidazoles were synthesized with a sulphur linkage. Thus, 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde (3) was prepared starting from simple salicylaldehyde which has been?used as an important synthon and incorporated in a series of structural manipulations to obtain various of pharmacophoric motif conjugates 9(a–b) and 13(a–f), in fair yields. We have developed facile and stepwise methods for the synthesis of all these compounds in various approaches, which also involves sub-sequences. All synthesized compounds were well characterized by IR, 1HNMR, 13CNMR and mass spectra data.

Synthesis, Photophysical and Computational Study of Novel Coumarin-based Organic Dyes

A series of novel coumarin pyrazoline moieties combined with tetrazoles, 3-(1-phenyl-4-(1H-tetrazol-5-yl)-1H-pyrazol-3-yl)-2H-chromen-2-one, 6-chloro-3-(1-phenyl-4-(1H-tetrazol-5-yl)-1H-pyrazol-3-yl)-2H-chromen-2-one, 6-bromo-3-(1-phenyl-4-(1H-tetrazol-5-

Instantaneous and Selective Bare Eye Detection of Inorganic Fluoride Ion by Coumarin–Pyrazole-Based Receptors

A series of rationally designed coumarin–pyrazole-based scaffolds, equipped with N―H and C―H hydrogen bond donors (R1–R5) and containing various electron-withdrawing groups at key positions, are synthesized and characterized in order to investigate their

3-(1-Phenyl-4-((2-(4-arylthiazol-2-yl)hydrazono)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-ones: One-pot three component condensation, in vitro antimicrobial, antioxidant and molecular docking studies

In an attempt to find a new class of heterocyclic bio-active agents, a series of novel 3-(1-phenyl-4-((2-(4-arylthiazol-2-yl)hydrazono)methyl)-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives (5a-l) have been synthesized efficiently both quantitatively and q

Synthesis and antimicrobial activity of coumarin pyrazole pyrimidine 2,4,6(1H,3H,5H)triones and thioxopyrimidine4,6(1H,5H)diones

A series of 5-((3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl) methylene)pyrimidine-2,4,6(1H,3H,5H)-trione (4a-f) and dihydro-5-((3-(2-oxo-2H- chromen-3-yl)-1-phenyl-1H-pyrazol-4-yl)methylene)-2-thioxopyrimidine-4,6(1H,5H) -dione (5a-f) derivatives w

Synthesis of some oxazolyl - Pyrazolyl; 1,4-dihydropyridinyl-pyrazolyl and 1,2,3,4-tetrahydro pyrimidinyl-pyrazolyl coumarins

(Chemical Equation Presented) Various 3-[1-phenyl-4-(2-substituted-5-oxo- oxazol-4-ylidenemethyl) pyrazol-3-yl] coumarins 4a-f; 3-[1-phenyl-4-(2,6- dimethyl-3,5-disubstituted-1,4-dihydropyridin-4-yl) pyrazol-3-yl] coumarins 5a-f and 3-[1-phenyl-4-(6-methy

4-Functionalized 3-Heterylpyrazoles. I. 4-Formyl-3-heterylpyrazoles

Vilsmeier-Haak reactions of 2-furyl, 2-thienyl, and 2-oxochromen-3-yl methyl ketones result in formation of the corresponding 4-formyl-3-heterylpyrazoles in high yield.