1036027-86-7

Usage

Uses

Used in Pharmaceutical Synthesis:
(R)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate is used as an intermediate in the synthesis of pharmaceuticals for its ability to be incorporated into the structure of various organic compounds, contributing to the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate is used as a building block for designing and developing new molecules with potential therapeutic properties, leveraging its biochemical compatibility and structural features.
Used in Drug Development:
(R)-tert-butyl 4-(1-aminoethyl)piperidine-1-carboxylate is utilized in drug development as a component in the creation of novel drug candidates, potentially leading to the discovery of new treatments for various diseases and conditions, given its capacity to engage with biological systems.

Upstream product

• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 455267-29-5 4-(1-amino-ethyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 1097880-26-6 tert-butyl 4-[(E)-{[(S)-2-methylpropane-2-sulfinyl]imino}methyl]piperidine-1-carboxylate 
• 1036027-89-0 C₈H₈O₃*C₁₂H₂₄N₂O₂ 

Downstream Products

• 1036027-91-4 tert-butyl 4-((1R)-1-(5-cyano-4-(1-tosyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-2-ylamino)ethyl)piperidine-1-carboxylate 
• 1802175-07-0 CPI-169 
• 1450655-12-5 (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(piperidin-4-yl)ethyl)-1H-indole-3-carboxamide 
• 1621862-70-1 CPI-1205 

Relevant academic research and scientific papers

MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE

Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. Formula I

IDO inhibitors

The invention discloses novel compounds used as indoleeamine-pyrrole-2,3-dioxygenase (IDO) inhibitors, and specifically discloses the compounds represented by a formula (I) shown in the description and pharmaceutically-acceptable salts of the compounds. The invention also discloses an application of the compounds represented by the formula (I) and the pharmaceutically-acceptable salts of the compounds in preparation of a medicament for treating tumors.

INDOLE DERIVATIVES AS MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents of formulas (l)/(ll)/(lll) for modulating methyl modifying enzymes, compositions and uses thereof are provided herein.

5-CYAN0-4- (PYRROLO [2, 3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.