455267-29-5

Usage

Uses

Used in Pharmaceutical Synthesis:
TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE is used as a building block in the pharmaceutical industry for the synthesis of drugs. Its unique structure allows it to be a key component in the development of new medications.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE is used as a research compound to study its interactions with neurotransmitters and receptors. This is due to its structural resemblance to key neurotransmitters, which may provide insights into the development of drugs targeting the nervous system.
Used in the Development of Bioactive Compounds:
TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE is utilized in the creation of bioactive compounds, which have potential applications in therapeutics and diagnostics. Its versatility in chemical modifications makes it a promising candidate for the design of molecules with specific biological activities.
Used in Neurotransmitter and Receptor Studies:
In the study of neurotransmitters and their receptors, TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE serves as a model compound. Its structural similarity to neurotransmitters like dopamine and serotonin aids researchers in understanding the mechanisms of neurotransmission and in developing drugs that can modulate these processes.
Used in the Development of New Chemical Entities:
TERT-BUTYL 4-(1-AMINOETHYL)PIPERIDINE-1-CARBOXYLATE is employed in the development of new chemical entities for various biological targets. Its potential applications span across different therapeutic areas, making it a valuable asset in the search for novel treatments and diagnostic tools.

Upstream product

• 7440-02-0 nickel 
• 206989-61-9 4-acetyl-1-(t-butoxycarbonyl)piperidine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 30818-11-2 1-(4-piperidinyl)ethanone 
• 1450658-46-4 tert-butyl 4-((S)-1-(1,1-dimethylethylsulfinamido)ethyl)piperidine-1-carboxylate 
• 137076-22-3 tert butyl 4-formylpiperidine-1-carboxylate 
• 1097880-26-6 tert-butyl 4-[(E)-{[(S)-2-methylpropane-2-sulfinyl]imino}methyl]piperidine-1-carboxylate 
• 139290-70-3 tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate 
• 84358-13-4 N-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid 
• 160809-34-7 4-acetyl-piperidine-1-carboxylic acid benzyl ester 
• 148148-48-5 4-(N-methoxy-N-methyl-carbamoyl)-piperidine-1-carboxylic acid benzyl ester 

Downstream Products

• 1036027-89-0 C₈H₈O₃*C₁₂H₂₄N₂O₂ 
• 1036027-88-9 C₈H₈O₃*C₁₂H₂₄N₂O₂ 
• 1428582-26-6 3-(cyclopropylmethoxy)-5-methoxy-N-(1-(piperidin-4-yl)ethyl)benzamide 2,2,2-trifluoroacetate 
• 1443004-98-5 N-(1-(1-(4-chloro-1,3,5-triazin-2-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1428581-57-0 N-(1-(1-(4-(3-cyanophenyl)-1,3,5-triazin-2-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1428582-27-7 N-(1-(1-(2-chloropyrimidin-4-yl)piperidin-4-yl)ethyl)-3-(cyclopropylmethoxy)-5-methoxybenzamide 
• 1621862-74-5 tert-butyl 4-(1-(3-(2-bromophenyl)-4-methoxy-4-oxobut-2-en-2-ylamino)ethyl)piperidine-1-carboxylate 
• 1036027-86-7 tert-butyl 4-[(1R)-1-aminoethyl]piperidine-1-carboxylate 

Relevant academic research and scientific papers

MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE

Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. Formula I

SMYD INHIBITORS

The present disclosure provides carboxamides and sulfonamides having Formula (I): and the pharmaceutically acceptable salts and solvates thereof, wherein A, Y, B, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.

ISOXAZOLE CARBOXAMIDE COMPOUNDS

The present disclosure provides substituted isoxazole carboxamide compounds having Formula (I) and the pharmaceutically acceptable salts and solvates thereof, wherein R1, R2, A, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

Agents having the structural Formula (II) for modulating histone methyl modifying enzymes, compositions and uses thereof for instance as anti-cancer agents are provided herein.

2′ Biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR

Biaryl amides were discovered as novel and subtype selective M1 muscarinic acetylcholine receptor agonists. The identification, synthesis, and initial structure-activity relationships that led to compounds 3j and 4c, possessing good M1 agonist potency and intrinsic activity, and subtype selectivity for M1 over M2-5, are described.

5-CYAN0-4- (PYRROLO [2, 3B] PYRIDINE-3-YL) -PYRIMIDINE DERIVATIVES USEFUL AS PROTEIN KINASE INHIBITORS

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

N-substituted nonaryl-heterocyclic NMDA/NR2B antagonists

Compounds represented by Formula (I): 1or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for relieving pain.