103615-48-1

Basic information

• Product Name: N-(tert-butyl)-2-IodoacetaMide
• Synonyms: N-(tert-butyl)-2-IodoacetaMide
• CAS NO: 103615-48-1
• Molecular Formula: C₆H₁₂INO
• Molecular Weight: 241.07005
• Mol File: 103615-48-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(tert-butyl)-2-IodoacetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butyl)-2-IodoacetaMide(103615-48-1)
• EPA Substance Registry System: N-(tert-butyl)-2-IodoacetaMide(103615-48-1)

Safety Data

• Hazardous Substances Data: 103615-48-1(Hazardous Substances Data)

Upstream product

• 15678-99-6 N-tert-butylchloroacetamide 
• 624-75-9 iodoacetonitrile 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 152607-49-3 N-tert-butyl 2-(3-bromo-2-oxo-5-phenyl-7-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 
• 152642-50-7 N-tert-butyl 2-(3-bromo-2-oxo-5-phenyl-8-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 
• 152607-64-2 N-tert-butyl 2-(3-bromo-2-oxo-5-(3-chlorophenyl)-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 
• 152607-72-2 N-tert-butyl 2-(3-bromo-2-oxo-5-phenyl-7-chloro-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 
• 167850-81-9 N-tert-butyl-2-(3-bromo-2-oxo-5-phenyl-8-ethyl-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 
• 152607-51-7 N-tert-butyl 2-(3-amino-2-oxo-5-phenyl-7-methyl-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)ethanoic acid amide 

Relevant articles and documents

Complexes of selected late period lanthanide(III) cations with 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl ligands-A new platform for the development of paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents

A series of 18 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid amide (DOTAM)-alkyl derived complexes with selected late lanthanide(III) cations (Dy3+, Tb3+, and Tm3+) has been synthesized; their magnetic properties have been evaluated and compared to those derived from DOTAM. Peralkylation of cyclen with corresponding N-iodoacetyl amines was utilized as the key step in the synthesis. Chemical exchange saturation transfer (CEST) spectra of the complexes have been acquired at 37 C, revealing that Tm3+-derived DOTAM-alkyl complexes possess the most favorable properties as potential paramagnetic chemical exchange saturation transfer (PARACEST) magnetic resonance imaging (MRI) contrast agents.

Safe and efficient ritter reactions in flow

Efficient mixing, temperature control and small environmental exposures allow reactions carried out in microfluidic de-vices to perform superior to their batch-type counterparts in conventional flasks. The Ritter reaction has been optimised for flow conditions leading to short reaction times and higher yields and also is more feasible with regards to safety, productivity and tolerance towards substrate functionalities.

5-Phenyl-3-ureidobenzazepin-2-ones as cholecystokinin-B receptor antagonists

A series of 5-phenyl-3-ureidobenzazepin-2-one cholecystokinin-B (CCK-B) receptor antagonists was synthesized using Beckmann ring expansion of a suitable 4-phenyl-1-tetralone as a key step. Structure-activity relationship studies revealed the importance of