1036389-83-9

Basic information

• Product Name: 2-BroMo-4-fluoro-5-nitrobenzoic Acid
• Synonyms: 2-BroMo-4-fluoro-5-nitrobenzoic Acid
• CAS NO: 1036389-83-9
• Molecular Formula: C₇H₃BrFNO₄
• Molecular Weight: 264.0054232
• Mol File: 1036389-83-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 379.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.967±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.25±0.12(Predicted)
• CAS DataBase Reference: 2-BroMo-4-fluoro-5-nitrobenzoic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BroMo-4-fluoro-5-nitrobenzoic Acid(1036389-83-9)
• EPA Substance Registry System: 2-BroMo-4-fluoro-5-nitrobenzoic Acid(1036389-83-9)

Safety Data

• Hazardous Substances Data: 1036389-83-9(Hazardous Substances Data)

Usage

Uses

2-Bromo-4-fluoro-5-nitrobenzoic Acid, is a halogenated derivative of benzoic acid. It can be used for the synthesis of various pharmaceutical compounds, such as amino acid derivatives acting as anticoagulants.

Upstream product

• 1006-41-3 2-bromo-4-fluorobenzoic acid 

Downstream Products

• 85953-31-7 2-bromo-4-fluoro-5-nitrobenzoic acid methyl ester 
• 1036389-88-4 5-amino-2-cyano-4-fluorobenzoate methyl ester 
• 1036389-90-8 6-amino-5-fluoro-isoindolin-1-one 
• 1036389-92-0 C₁₈H₁₇FN₂O₅ 
• 932374-77-1 1-bromo-5-fluoro-4-nitro-2-(trifluoromethyl)benzene 

Relevant articles and documents

SUBSTITUTED TRICYCLIC COMPOUNDS

Disclosed are compounds of the general formula (I), its tautomeric form, its stereoisomer, its pharmaceutically acceptable salt, its polymorph, or solvate thereof, wherein, ring A, ring B, R1 to R4, and n are as defined herein, for use as SOS1 inhibitors in the treatment of proliferative, infectious and RASopathy diseases or disorders. Also disclosed are methods of synthesizing the compound of formula I, pharmaceutical compositions containing the compound of formula I, method of treatment of proliferative, infectious and RASopathy diseases or disorder, for example, a cancer, by administering the said compound and combinations of the compound of formula I with other active ingredients.

CARBOXYLIC ACID AROMATIC 1,2-CYCLOPROPYLAMIDES

The present invention relates to carboxylic acid aromatic 1,2-cyclopropylamides of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of neurogenic disorder, as a sole agent or in combination with other active ingredients.

cGAS ANTAGONIST COMPOUNDS

Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.