1036389-86-2

Basic information

• Product Name: 5-AMino-2-broMo-4-fluorobenzoic Acid Methyl Ester
• Synonyms: 5-AMino-2-broMo-4-fluorobenzoic Acid Methyl Ester
• CAS NO: 1036389-86-2
• Molecular Formula: C₈H₇BrFNO₂
• Molecular Weight: 248.0490832
• Product Categories: Aromatics, Miscellaneous Reagents
• Mol File: 1036389-86-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-AMino-2-broMo-4-fluorobenzoic Acid Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMino-2-broMo-4-fluorobenzoic Acid Methyl Ester(1036389-86-2)
• EPA Substance Registry System: 5-AMino-2-broMo-4-fluorobenzoic Acid Methyl Ester(1036389-86-2)

Safety Data

• Hazardous Substances Data: 1036389-86-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester is used as a key intermediate in the synthesis of lactam amino acid derivatives with anti-coagulant activity. These derivatives have the potential to be developed into novel therapeutic agents for the prevention and treatment of blood clot-related disorders, such as deep vein thrombosis, pulmonary embolism, and stroke.
In the synthesis process, 5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester serves as a building block for the formation of lactam rings, which are essential structural components of many bioactive compounds. The presence of the bromine and fluorine atoms in the molecule can also contribute to the modulation of the biological activity and selectivity of the resulting lactam amino acid derivatives.
Furthermore, the versatility of 5-Amino-2-bromo-4-fluorobenzoic Acid Methyl Ester allows for the development of a range of structurally diverse lactam amino acid derivatives with varying anti-coagulant properties. This can lead to the discovery of more effective and safer anti-coagulant drugs, addressing the unmet medical needs in the prevention and treatment of blood clot-related conditions.

Upstream product

• 1006-41-3 2-bromo-4-fluorobenzoic acid 
• 85953-31-7 2-bromo-4-fluoro-5-nitrobenzoic acid methyl ester 

Downstream Products

• 1036389-90-8 6-amino-5-fluoro-isoindolin-1-one 
• 1036389-92-0 C₁₈H₁₇FN₂O₅ 
• 1036389-88-4 5-amino-2-cyano-4-fluorobenzoate methyl ester 

Relevant articles and documents

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