10364-67-7 Usage
Uses
Used in Pharmaceutical Development:
3-(4-Nitrophenyl)-5-propyl-1,2,4-oxadiazole is used as a building block in the synthesis of pharmaceuticals for its potential to contribute to the development of biologically active compounds. Its unique structure allows for the creation of new drugs with specific therapeutic properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 3-(4-Nitrophenyl)-5-propyl-1,2,4-oxadiazole is utilized as a research compound to explore its interactions with biological targets. Its chemical properties make it an interesting subject for studying its potential effects on various diseases and conditions.
Used in Chemical Synthesis Industry:
3-(4-Nitrophenyl)-5-propyl-1,2,4-oxadiazole is employed as an intermediate in the synthesis of various organic compounds. Its versatile structure allows it to be a key component in the production of specialty chemicals used in different industries.
Used in Material Science:
3-(4-NITROPHENYL)-5-PROPYL-1,2,4-OXADIAZOLE may also find applications in material science, where its unique properties could be leveraged to develop new materials with specific characteristics, such as improved stability or reactivity in certain conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 10364-67-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,6 and 4 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10364-67:
(7*1)+(6*0)+(5*3)+(4*6)+(3*4)+(2*6)+(1*7)=77
77 % 10 = 7
So 10364-67-7 is a valid CAS Registry Number.
10364-67-7Relevant academic research and scientific papers
Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides
Conole, Daniel,Beck, Thorsten M.,Jay-Smith, Morgan,Tingle, Malcolm D.,Eason, Charles T.,Brimble, Margaret A.,Rennison, David
, p. 2220 - 2235 (2014/04/17)
A number of isosteres (oxadiazoles, thiadiazoles, tetrazoles and diazines) of benzocaine were prepared and evaluated for their capacity to induce methemoglobinemia - with a view to their possible application as humane pest control agents. It was found that an optimal lipophilicity for the formation of methemoglobin (metHb) in vitro existed within each series, with 1,2,4-oxadiazole 3 (metHb% = 61.0 ± 3.6) and 1,3,4-oxadiazole 10 (metHb% = 52.4 ± 0.9) demonstrating the greatest activity. Of the 5 candidates (compounds 3, 10, 11, 13 and 23) evaluated in vivo, failure to induce a lethal end-point at doses of 120 mg/kg was observed in all cases. Inadequate metabolic stability, particularly towards hepatic enzymes such as the CYPs, was postulated as one reason for their failure.
