103653-53-8Relevant academic research and scientific papers
TAUTOMERISM IN THE SERIES OF METHYL 5,5-DIMETHYL-2,4-DIOXOHEXANOATE ACYLHYDRAZONES
Yakimovich, S. I.,Nikolaev, V. N.,Zerova, I. V.
, p. 250 - 255 (2007/10/02)
It was shown by PMR spectroscopy that methyl 5,5-dimethyl-2,4-dioxohexanoate acylhydrazones exist in solutions as mixtures of the geometric isomers of the hydrazone and cyclic 5-hydroxypyrazoline forms.In the series of aroylhydrazones the introduction of electron-withdrawing substituents into the aromatic ring of the N-aroyl radical shifts the ring-chain equilibrium slightly toward the 5-hydroxypyrazoline tautomer.In the series of products from condensation with the hydrazides of aliphatic acids increase in the size of the substituents in the acyl part favors the open-chain hydrazone form.
