1036539-29-3

Basic information

• Product Name: 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylic acid
• Synonyms: 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylic acid
• CAS NO: 1036539-29-3
• Molecular Weight: 286.718
• Mol File: 1036539-29-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylic acid(1036539-29-3)
• EPA Substance Registry System: 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylic acid(1036539-29-3)

Safety Data

• Hazardous Substances Data: 1036539-29-3(Hazardous Substances Data)

Upstream product

• 1168139-13-6 methyl 1-(4-chlorobenzyl)-1H-benzo[d]imidazole-5-carboxylate 
• 174422-22-1 methyl 4-(4-chlorobenzylamine)-3-nitrobenzoic acid ester 
• 453-71-4 3-nitro-4-fluorobenzoic acid 
• 329-59-9 4-fluoro-3-nitro-benzoic acid methyl ester 

Downstream Products

• 1438983-62-0 (S)-1-(4-chlorobenzyl)-N-(1-(3-isopropylphenyl)ethyl)-1H-benzo[d]imidazole-5-carboxamide 

Relevant articles and documents

N-BENZYLBENZIMIDAZOLE MODULATORS OF PPARG

The invention provides molecular entities that bind with high affinity to PPARG (PPAR?), inhibit cdk5-mediated phosphorylation of PPARG, but do not exert an agonistic effect on PPARG. Compounds of the invention can be used for treatment of conditions in patients wherein PPARG plays a role, such as diabetes or obesity. Methods of preparation of the compounds, bioassay methods for evaluating compounds of the invention as non-agonistic PPARG binding compounds, and pharmaceutical compositions are also provided.