103654-51-9

Basic information

• Product Name: hormothamnione triacetate
• Synonyms: hormothamnione triacetate
• CAS NO: 103654-51-9
• Molecular Weight: 526.497
• Mol File: 103654-51-9.mol

Chemical Properties

• CAS DataBase Reference: hormothamnione triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: hormothamnione triacetate(103654-51-9)
• EPA Substance Registry System: hormothamnione triacetate(103654-51-9)

Safety Data

• Hazardous Substances Data: 103654-51-9(Hazardous Substances Data)

Upstream product

• 65884-12-0 2,3,4,5-tetramethoxybenzaldehyde 
• 30225-99-1 2,3,4,5-Tetramethoxyphenol 
• 13909-75-6 1,2,3,4,5-pentamethoxybenzene 
• 21450-56-6 1,2,3,4-tetramethoxybenzene 
• 119232-80-3 2,5-dihydroxy-3,4,6-trimethoxypropiophenone 
• 117970-67-9 2,3-dimethyl-5,6,7,8-tetramethoxy chromone 
• 117970-66-8 2-hydroxy-3,4,5,6-tetramethoxy propiophenone 
• 117970-68-0 5,6,7,8-Tetramethoxy-2-<2-<3,5-bis(benzyloxy)phenyl>ethenyl>-3-methylchromone 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 14615-72-6 3,5-dibenzyloxybenzaldehyde 
• 103654-49-5 Hormothamnione 
• 108-24-7 acetic anhydride 

Downstream Products

• 103654-49-5 Hormothamnione 

Relevant articles and documents

Hormothamnione, a novel cytotoxic styrylchromone from the marine cyanophyte Hormothamnion enteromorphoides Grunow

The first naturally occurring styrylchromone, hormothamnione, was isolated from the marine cyanophyte Hormothamnion enteromorphoides and its structure determined by an x-ray experiment on its triacetate derivative. Hormothamnione is an exceptionally potent cytotoxin to cancer cells in vitro and appears to be a selective inhibitor of RNA synthesis.

SYNTHESIS OF HORMOTHAMNIONE

Hormothamnione 1 has been obtained from 2,3-dimethyl-5,6,7,8-tetramethoxy-chromone 18 in 63percent yield.Synthesis of the required chromone 18 as well as of the 2 and 3-styryl analogs 5 and 9 are described.