14615-72-6

Basic information

• Product Name: 3,5-Dibenzyloxybenzaldehyde
• Synonyms: 3,5-BENZYLOXY BENZALDEHYDE;3,5-BIS(BENZYLOXY)BENZALDEHYDE;3,5-DIBENZYLOXYBENZALDEHYDE;TIMTEC-BB SBB008628;3,5-DibroMobenzaldehyde, 95+%
• CAS NO: 14615-72-6
• Molecular Formula: C₂₁H₁₈O₃
• Molecular Weight: 318.37
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Building Blocks for Dendrimers;Functional Materials;Aldehydes;C10 to C21;Carbonyl Compounds
• Mol File: 14615-72-6.mol
• Article Data: 29

Chemical Properties

• Melting Point: 78-80 °C(lit.)
• Boiling Point: 502.4 °C at 760 mmHg
• Flash Point: 250 °C
• Appearance: orange to orange-tan powder or crystalline powder
• Density: 1.176 g/cm³
• Vapor Pressure: 0.00252mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• CAS DataBase Reference: 3,5-Dibenzyloxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dibenzyloxybenzaldehyde(14615-72-6)
• EPA Substance Registry System: 3,5-Dibenzyloxybenzaldehyde(14615-72-6)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 14615-72-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 14615-72-6 differently. You can refer to the following data:
1. 3,5-Dibenzyloxybenzaldehyde is a useful research chemical.
2. 3,5-Dibenzyloxybenzaldehyde may be used in the synthesis of survivin dimerization modulators.

InChI:InChI=1/C7H4Br2O/c8-6-1-5(4-10)2-7(9)3-6/h1-4H

Upstream product

• 100-44-7 benzyl chloride 
• 50513-72-9 (3,5-di-benzyloxy)benzoic acid benzyl ester 
• 100-39-0 benzyl bromide 
• 29654-55-5 5-(hydroxymethyl)benzene-1,3-diol 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 26153-38-8 3,5-dihydroxybenzaldehyde 
• 85565-94-2 2-bromo-3,5-bis(benzyloxy)benzaldehyde 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 

Downstream Products

• 74346-08-0 (2E,4E)-methyl 2-carboxy-5-(3,5-dibenzyloxyphenyl)penta-2,4-dienoate 
• 117970-58-8 2-[(E)-2-(3,5-Bis-benzyloxy-phenyl)-vinyl]-3-methyl-chromen-4-one 
• 50841-47-9 3,5-dibenzilossi-1-epossietilbenzene 
• 117970-68-0 5,6,7,8-Tetramethoxy-2-<2-<3,5-bis(benzyloxy)phenyl>ethenyl>-3-methylchromone 
• 128191-02-6 5,6,7-Trimethoxy-2-<2-<3,5-bis(benzyloxy)phenyl>ethenyl>chromone 
• 50545-12-5 3,5-Di(benzyloxy)-β-nitrostyrol 
• 937175-36-5 (E)-3-(3,5-Bis-benzyloxy-phenyl)-acrylic acid ethyl ester 
• 186136-11-8 4-[(E)-2-(3,5-Bis-benzyloxy-phenyl)-vinyl]-benzoic acid methyl ester 
• 86255-44-9 (E)-(((5-(2-nitrovinyl)-1,3-phenylene)bis(oxy))bis(methylene))dibenzene 
• 184375-00-6 1-(3',5'-dibenzyloxyphenyl)-2-nitronon-1-ene 
• 193617-75-3 1-(3',5'-dibenzyloxyphenyl)-2-nitrohept-1-ene 
• 185254-53-9 (((5-vinyl-1,3-phenylene)bis(oxy))bis(methylene))dibenzene 
• 64793-97-1 3-(3,5-dibenzyloxyphenyl)-propanic acid 
• 186136-24-3 (Z)-3-(3,5-Bis-benzyloxy-phenyl)-acrylic acid ethyl ester 

Relevant articles and documents

Bis(benzylamine) monomers: One-pot preparation and application in dendrimer scaffolds for removing pyrene from aqueous environments

Bisimine and bisamine AB2 monomers have been synthesized from 3,5-diaminobenzoic acid and benzaldehyde derivatives without the need for protective groups or purification. This monomer preparation is universal for various electron-donating and electronwith

Design and synthesis of π-extended resveratrol analogues and in vitro antioxidant and anti-inflammatory activity evaluation

The research on resveratrol (1) has been conducted intensively over a long time due to its proven antioxidant activity and disease-fighting capabilities. Many efforts have also been made to increase these biological effects. In the present study, six new extended aromatic resveratrol analogues containing naphthalene (2) and its bioisosteres quinoline (3 and 4), isoquinoline (5) quinoxaline (6) and quinazoline (7) scaffolds were designed and synthesized using an annulation strategy. The antioxidant and anti-inflammatory activities of these compounds were investigated. All compounds showed better antioxidant activity than resveratrol in ABTS assay. As for the anti-inflammatory test, 5 and 7 exhibited better activity than resveratrol. It is worth noting that nitrogen substitution on the extended aromatic resveratrol analogues has a significant impact on cell viability. Taking the antioxidant activities and NO inhibition activities into consideration, we conclude that isoquinoline analogue 5 may qualify for the further investigation of antioxidant and anti-inflammatory therapy. Furthermore, our study results suggest that in order to improve the biological activity of polyphenolic compounds, extended aromaticity and nitrogen substitution strategy could be a viable method for the design of future drug candidates.

CO2-Catalyzed oxidation of benzylic and allylic alcohols with DMSO

CO2-catalyzed transition-metal-free oxidation of alcohols has been achieved. Earlier, several methodologies have been explored for alcohol oxidations based on transition-metal catalysts. However, owing to the cheaper price, easy separation and nontoxicity, transition-metal-free systems are in high demand to the pharmaceutical industries. For this reason, various primary and secondary alcohols have been selectively oxidized to the corresponding carbonyl compounds using CO2 as a catalyst in the presence of different functional groups such as nitrile, nitro, aldehyde, ester, halogen, ether, and so on. At the end, transition-metal-free syntheses of pharmaceuticals have also been achieved. Finally, the role of CO2 has been investigated in detail, and the mechanism is proposed on the basis of experiments and DFT calculations.