103654-87-1

Basic information

• Product Name: N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-4-hydroxyproline ethyl ester
• Synonyms: N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-4-hydroxyproline ethyl ester
• CAS NO: 103654-87-1
• Molecular Weight: 595.905
• Mol File: 103654-87-1.mol

Chemical Properties

• CAS DataBase Reference: N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-4-hydroxyproline ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-4-hydroxyproline ethyl ester(103654-87-1)
• EPA Substance Registry System: N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-4-hydroxyproline ethyl ester(103654-87-1)

Safety Data

• Hazardous Substances Data: 103654-87-1(Hazardous Substances Data)

Upstream product

• 92893-51-1 (S)-2-[((S)-1-Chlorocarbonyl-ethyl)-(2,2,2-trichloro-ethoxycarbonyl)-amino]-4-phenyl-butyric acid ethyl ester 
• 33996-30-4 trans-4-hydroxy-L-proline ethyl ester hydrochloride 
• 92893-50-0 N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-N-(2,2,2-trichloroethoxycarbonyl)-L-alanine 

Downstream Products

• 103580-24-1 N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-L-prolin-4-one ethyl ester 
• 126257-62-3 N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-(4S)-4-amino-L-proline ethyl ester 
• 126257-61-2 N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-(4S)-4-azido-L-proline ethyl ester 
• 126257-69-0 N--L-alanyl>-4-2-(3-sulfamyl-4-chlorobenzoyl)hydrazino>-L-proline ethyl ester 
• 126373-61-3 1'--L-alanyl>-5'-(ethoxycarbonyl)-7-(aminosulfonyl)-6-chlorospiro-<2H-1,2,4-benzothiadiazine-3(4H),3'-pyrrolidine> S,S-dioxide 
• 126257-64-5 N--L-alanyl>-(4S)-4-<<<6-chloro-1,2,4-benzothiadiazin-7-yl>sulfonyl>amino>-L-proline ethyl ester S,S-dioxide 
• 103580-39-8 N--L-alanyl>-(4RS)-4--N-methylamino>-L-proline ethyl ester S,S-dioxide 
• 103580-37-6 N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-4-2-(3-sulfamyl-4-chlorobenzoyl)hydrazino>-L-proline ethyl ester 
• 103632-12-8 1'--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-5'-(ethoxycarbonyl)-7-(aminosulfonyl)-6-chlorospiro-<2H-1,2,4-benzothiadiazine-3(4H),3'-pyrrolidine> S,S-dioxide 
• 126257-63-4 N--N'-<(2,2,2-trichloroethoxy)carbonyl>-L-alanyl>-(4S)-4-<<<6-chloro-1,2,4-benzothiadiazin-7-yl>sulfonyl>amino>-L-proline ethyl ester S,S-dioxide 
• 126373-75-9 1'-[N'-((1S)-1-carboxy-3-phenylpropyl)-L-alanyl]-5'-carboxy-7-(aminosulfonyl)-6-chlorospiro(2H-1,2,4-benzothiadiazine-3(4H),3'-pyrrolidine) S,S-dioxide 
• 126373-74-8 N-[N'-((1S)-1-carboxy-3-phenylpropyl)-L-alanyl]-(4S)-4-{[(6-chloro-1,2,4-benzothiadiazin-7-yl)sulfonyl]amino}-L-proline S,S-dioxide 
• 103580-40-1 N--L-alanyl>-(4RS)-4--N-methylamino>-L-proline S,S-dioxide 
• 103665-12-9 N-[N'-((1S)-1-carboxy-3-phenylpropyl)-L-alanyl]-4-[N²-(3-sulfamyl-4-chlorobenzoyl)hydrazino]-L-proline 

Relevant articles and documents

Angiotensin converting enzyme inhibitors. 10. Aryl sulfonamide substituted N-[1-carboxy-3-phenylpropyl]-L-alanyl-L-proline derivatives as novel antihypertensives

Compounds 1a-g consisting of enalaprilat covalently bonded to aryl sulfonamides, including several known thiazide diuretics, were synthesized and tested for ACE inhibitory and diuretic and overall antihypertensive effects. All compounds were potent ACE in