103664-41-1

Basic information

• Product Name: (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran
• Synonyms: (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran
• CAS NO: 103664-41-1
• Molecular Weight: 242.057
• Mol File: 103664-41-1.mol

Chemical Properties

• CAS DataBase Reference: (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran(103664-41-1)
• EPA Substance Registry System: (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran(103664-41-1)

Safety Data

• Hazardous Substances Data: 103664-41-1(Hazardous Substances Data)

Upstream product

• 32780-06-6 (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran 

Downstream Products

• 24570-49-8 (+)-muscarine iodide 
• 2303-35-7 (+)-muscarine chloride 
• 104487-60-7 L-(+)-muscarine tetraphenylborate 
• 326805-91-8 (-)-(2S,4R,5S)-2-[(Dimethylamino)methyl]-4-benzyloxy-5-methyltetrahydrofuran 
• 326805-89-4 (-)-(2S,4R,5S)-2-(Iodomethyl)-4-benzyloxy-5-methyltetrahydrofuran 

Relevant articles and documents

A concise asymmetric synthesis of (+)-muscarine from (S)-γ-hydroxymethyl-γ-butyrolactone

A highly stereoselective synthesis of (+)-muscarine iodide has been achieved in eight steps and 20% overall yield from commercially available (S)-γ-hydroxymethyl-γ-butyrolactone.