2303-35-7

Usage

Uses

(+)-Muscarine Chloride modulates calcium channel currents in rats.

InChI:InChI=1/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/t7?,8-,9?;/m0./s1

Upstream product

• 104048-27-3 (+/-)-epiallo-muscarine iodide 
• 24570-49-8 (+)-muscarine iodide 
• 75499-85-3 2,5:3,4-dianhydro-1-O-p-tolylsulphonyl-D-allitol 
• 75499-87-5 2,5-anhydro-4,6-di-O-benzoyl-1-chloro-1-deoxy-D-glucitol 
• 75499-83-1 2,5-anhydro-4,5-di-O-benzoyl-D-glucitol 
• 124251-98-5 (S)-3-(2-Benzyloxy-ethoxy)-1-diazo-butan-2-one 
• 124251-97-4 (S)-2-(2-Benzyloxy-ethoxy)-propionic acid 
• 123990-91-0 (S)-5-Benzyloxymethyl-2-methyl-dihydro-furan-3-one 
• 75499-88-6 2,5-anhydro-4,6-di-O-benzoyl-1-deoxy-D-glucitol 
• 75499-86-4 (2S,4R,5S)-(4-hydroxy-5-methyltetrahydrofuran-2-yl)methanol 
• 103664-41-1 (-)-(2S,4R,5S)-2-(Iodomethyl)-4-hydroxy-5-methyltetrahydrofuran 
• 75499-91-1 2,5-anhydro-1,4-dideoxy-6-O-(p-tolylsulphonyl)-D-ribo-hexitol 
• 75-50-3 trimethylamine 
• 501-37-1 (+/-)-epiallonormuscarine 

Downstream Products

• 108192-52-5 (+/-)-allomuscarone; tetraphenyl borate 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF THE MUSCARINES

The total syntheses of racemic muscarine and allo-muscarine have been achieved using as a key step the stereospecific photochemical ring expansion of a cyclobutanone.

Chelation-Controlled Synthesis of (+/-)-Muscarine

The chelation controlled addition of Grignard reagents to chiral α-alkoxy aldehydes to give threo diol derivatives is synthetically useful in highly oxygenated systems and is used here as the key step in a novel synthesis of (+/-)-muscarine from cyclopentadiene.