1036724-54-5Relevant articles and documents
2-AZABICYCLO HEXANE JAK INHIBITOR COMPOUND
-
Paragraph 0155, (2020/05/14)
The invention provides a compound of formula 1 or a pharmaceutically-acceptable salt thereof, that is useful as a JAK inhibitor. The invention also provides pharmaceutical compositions comprising the compound, methods of using the compound to treat diseas
Regioselectivity of fluorine substitution by alkoxides on unsymmetrical difluoroarenes
Dirr, Ronan,Anthaume, Cyril,Désaubry, Laurent
, p. 4588 - 4590 (2008/09/21)
An efficient approach to unsymmetrical halogenated resorcinol diethers has been developed. This synthesis consists of two subsequent nucleophilic aromatic substitutions (SNAr) of unsymmetrical difluoroarenes by alkoxides. The novelty of this ap