1036740-44-9Relevant academic research and scientific papers
2-Aminobenzophenones as a novel class of bradykinin B1 receptor antagonists
Su, Dai-Shi,Lim, John L.,Tinney, Elizabeth,Wan, Bang-Lin,Murphy, Kathy L.,Reiss, Duane R.,Harrell, C. Meacham,O'Malley, Stacy S.,Ransom, Rick W.,Chang, Raymond S. L.,Pettibone, Douglas J.,Yu, Jian,Tang, Cuyue,Prueksaritanont, Thomayant,Freidinger, Roger M.,Bock, Mark G.,Anthony, Neville J.
, p. 3946 - 3952 (2008)
Selective bradykinin (BK) B1 receptor antagonists could be novel therapeutic agents for the treatment of pain and inflammation. Elucidation of the structure activity relationships of the structurally novel HTS lead compound 1 provided potent hBK B1 receptor antagonists with excellent receptor occupancy in the CNS of hBK B1 transgenic rats.
