Journal of Medicinal Chemistry p. 3946 - 3952 (2008)
Update date:2022-07-30
Topics:
Su, Dai-Shi
Lim, John L.
Tinney, Elizabeth
Wan, Bang-Lin
Murphy, Kathy L.
Reiss, Duane R.
Harrell, C. Meacham
O'Malley, Stacy S.
Ransom, Rick W.
Chang, Raymond S. L.
Pettibone, Douglas J.
Yu, Jian
Tang, Cuyue
Prueksaritanont, Thomayant
Freidinger, Roger M.
Bock, Mark G.
Anthony, Neville J.
Selective bradykinin (BK) B1 receptor antagonists could be novel therapeutic agents for the treatment of pain and inflammation. Elucidation of the structure activity relationships of the structurally novel HTS lead compound 1 provided potent hBK B1 receptor antagonists with excellent receptor occupancy in the CNS of hBK B1 transgenic rats.
View MoreChemieliva Pharmaceutical Co., Ltd.
website:http://www.chemieliva.com
Contact:+86-23-67770219
Address:99 Longhua Road, Yubei District, 401147, Chongqing, China Email: sales@chemieliva.com Tel:0086-23-67770219 Fax: 0086-23-67770220 Attn: Andy Huang
Beijing Cooperate Pharmaceutical Co.,Ltd
website:http://www.cooperate-pharm.com/
Contact:86-01060279497
Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Contact:86-931-8272767
Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Hangzhou innopharma technology Co,.Ltd.(expird)
Contact:+86-13388601988
Address:Room845,lixin building, moganshan road, hangzhou, china
Nanjing Chemipioneer Pharma&Tech Co.,Ltd
website:http://www.chemipioneer.com.cn
Contact:+86-25-52685700
Address:Room 305，A Block，Biological-Medicine Building，Business Start-up Center，Xin-ke 1st Road, High-tech development zone，Nanjing city，Jiangsu Province, China
Doi:10.1039/C8NJ04493G
(2019)Doi:10.1016/j.cclet.2010.12.048
(2011)Doi:10.1016/j.tet.2008.03.091
(2008)Doi:10.1016/j.bmc.2008.04.004
(2008)Doi:10.1248/cpb.34.1634
(1986)Doi:10.1021/jo101917x
(2011)
