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Methyl 2-chloroquinazolin-4-carboxylate is a quinazoline derivative, a class of organic compounds characterized by the fusion of a benzene and a pyrimidine ring. This specific compound is distinguished by the presence of a chlorine atom at the 2-position and a carboxy group at the 4-position. It is known for its utility in the synthesis of pharmaceutical compounds, although its potential toxicity is a consideration.

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  • 1036755-96-0 Structure
  • Basic information

    1. Product Name: Methyl 2-chloroquinazolin...
    2. Synonyms: Methyl 2-chloroquinazolin...;6-Quinazolinecarboxylic acid, 2-chloro-, Methyl ester;Methyl 2-chloroquinazoline-6-carboxylate;Methyl 2-chloro-quinazolin-6-carboxylate
    3. CAS NO:1036755-96-0
    4. Molecular Formula: C10H7ClN2O2
    5. Molecular Weight: 222.62778
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1036755-96-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Methyl 2-chloroquinazolin...(CAS DataBase Reference)
    10. NIST Chemistry Reference: Methyl 2-chloroquinazolin...(1036755-96-0)
    11. EPA Substance Registry System: Methyl 2-chloroquinazolin...(1036755-96-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1036755-96-0(Hazardous Substances Data)

1036755-96-0 Usage

Uses

Used in Pharmaceutical Synthesis:
Methyl 2-chloroquinazolin-4-carboxylate is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its chemical structure allows for the creation of a wide range of drug molecules, making it a valuable component in the development of new medications.
Used in Research and Development:
In the field of medicinal chemistry, Methyl 2-chloroquinazolin-4-carboxylate serves as a model compound for studying the properties and potential applications of quinazoline derivatives. This helps researchers understand how these compounds interact with biological systems and can be modified for therapeutic use.
Used in Drug Design:
Methyl 2-chloroquinazolin-4-carboxylate is used as a building block in drug design, where its unique structure can be exploited to create new molecules with desired pharmacological properties. Its versatility in chemical reactions makes it a popular choice for the development of novel therapeutic agents.
Used in Toxicological Studies:
Due to its noted potential toxicity, Methyl 2-chloroquinazolin-4-carboxylate is also used in toxicological research to understand the mechanisms of action and potential adverse effects associated with quinazoline compounds. This information is crucial for the safe development and use of pharmaceuticals derived from this class of compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 1036755-96-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,6,7,5 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1036755-96:
(9*1)+(8*0)+(7*3)+(6*6)+(5*7)+(4*5)+(3*5)+(2*9)+(1*6)=160
160 % 10 = 0
So 1036755-96-0 is a valid CAS Registry Number.

1036755-96-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 2-chloroquinazoline-6-carboxylate

1.2 Other means of identification

Product number -
Other names methyl 2-chloroquinazolin-6-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1036755-96-0 SDS

1036755-96-0Relevant articles and documents

INHIBITORS OF ENL/AF9 YEATS

-

Paragraph 00203; 00206, (2021/06/26)

Methods and compositions for treating leukemia are disclosed. Acylated 6-aminoindoles, acylated 6-aminopyrrolopyridines and acylated 3-aminopyrrolo[3,2-c]pyridazines of the following formula inhibit ENL/AF9 YEATS and are therefore useful for treating leukemia.

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