103680-83-7

Basic information

• Product Name: 4'-ethoxymethoxy-2'-hydroxy-α-hydroxymethyl-4-methoxydihydrochalcone
• Synonyms: 4'-ethoxymethoxy-2'-hydroxy-α-hydroxymethyl-4-methoxydihydrochalcone
• CAS NO: 103680-83-7
• Molecular Weight: 360.407
• Mol File: 103680-83-7.mol

Chemical Properties

• CAS DataBase Reference: 4'-ethoxymethoxy-2'-hydroxy-α-hydroxymethyl-4-methoxydihydrochalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-ethoxymethoxy-2'-hydroxy-α-hydroxymethyl-4-methoxydihydrochalcone(103680-83-7)
• EPA Substance Registry System: 4'-ethoxymethoxy-2'-hydroxy-α-hydroxymethyl-4-methoxydihydrochalcone(103680-83-7)

Safety Data

• Hazardous Substances Data: 103680-83-7(Hazardous Substances Data)

Upstream product

• 104311-10-6 4'-ethoxymethoxy-2'-hydroxy-4-methoxy-dihydrochalcone 
• 3188-13-4 ethyl chloromethyl ether 
• 93435-21-3 1-(2,4-dihydroxyphenyl)-3-(4-methoxyphenyl)propane-1-one 
• 81674-92-2 (E)-1-(4-(benzyloxy)-2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 

Downstream Products

• 103680-87-1 3-(4-methoxy)-benzyl-7-hydroxy-4-chromanone 
• 103680-85-9 3-(4-methoxy) benzyl, 7-ethoxymethoxy-4-chromanone 

Relevant articles and documents

A New Synthesis of Homoisoflavanones (3-Benzyl-4-chromanones)

7-Hydroxy-4'-methoxyhomoisoflavanone (5) has been synthesised from 2',4'-dihydroxy-4-methoxydihydrochalcone (1) by a new method involving ethoxymethylation of 4'-hydroxyl group to give 2, followed by hydroxymethylation of the bridge methylene in 2, heterocyclization of 3 and deprotection of 4.

A NEW SYNTHESIS OF HOMOISOFLAVANONES (3-BENZYL-4-CHROMANONES)

Two 7-hydroxyhomoisoflavanones (6a/6b) have been synthesized from corresponding 2'-hydroxydihydrochalcones (2a/2b) in about 33percent overall yields.The stages are : (i) selective protection of C4'-hydroxyl in 2a/2b with EtO.CH2Cl (1 molar equiv.) in the