103698-40-4Relevant academic research and scientific papers
The Invention of Radical Reactions. XXXIII Homologation Reactions of Carboxylic Acids by Radical Chain Chemistry
Barton, Derek H. R.,Chern, Ching-Yuh,Jaszberenyi, Joseph Cs.
, p. 407 - 426 (2007/10/02)
Various carbon radicals can be generated from carboxylic acids via the corresponding Barton esters.These radicals can be used for the synthesis of longer chain homologues of the original acids.
Decarboxylative radical addition to vinylsulphones and vinylphosphonium bromide: Some further novel transformations of geminal (pyridine-2-thiyl) phenylsulphones
Barton,Boivin,Crepon nee da Silva,Sarma,Togo,Zard
, p. 7091 - 7108 (2007/10/02)
Irradiation of O-acyl derivatives 1 of N-hydroxy-2-thiopyridone with visible light in the presence of phenyl vinyl sulphone or vinyl triphenylphosphonium bromide leads to the corresponding adducts 8 and 9 which can undergo a wide variety of further transformations.
HOMOLOGATION OF ACIDS via CARBON RADICALS GENERATED FROM THE ACYL DERIVATIVES OF N-HYDROXY-2-THIOPYRIDONE. (THE TWO-CARBON PROBLEM).
Barton, Derek H. R.,Chern, Ching-Yuh,Jaszberenyi, Joseph Cs.
, p. 3309 - 3312 (2007/10/02)
Reaction of suitable substituted olefins with carbon radicals generated from the acyl derivatives of N-hydroxy-2-thiopyridone results in the formation of precursors for the corresponding homo-acids.These compounds can then be transformed to the desired end-products in high yield under mild conditions.
RADICAL ADDITION TO VINYL SULPHONES AND VINYL PHOSPHONIUM SALTS
Barton, Derek H. R.,Togo, Hideo,Zard, Samir Z.
, p. 6349 - 6352 (2007/10/02)
Alkyl radicals, derived from decarboxylation of carboxylic acids, add readily to phenyl vinyl sulphone and vinyl phosphonium bromide.The adducts may be further converted into a variety of useful synthetic intermediates.
