135967-06-5Relevant academic research and scientific papers
The Invention of Radical Reactions. XXXIII Homologation Reactions of Carboxylic Acids by Radical Chain Chemistry
Barton, Derek H. R.,Chern, Ching-Yuh,Jaszberenyi, Joseph Cs.
, p. 407 - 426 (2007/10/02)
Various carbon radicals can be generated from carboxylic acids via the corresponding Barton esters.These radicals can be used for the synthesis of longer chain homologues of the original acids.
HOMOLOGATION OF ACIDS via CARBON RADICALS GENERATED FROM THE ACYL DERIVATIVES OF N-HYDROXY-2-THIOPYRIDONE. (THE TWO-CARBON PROBLEM).
Barton, Derek H. R.,Chern, Ching-Yuh,Jaszberenyi, Joseph Cs.
, p. 3309 - 3312 (2007/10/02)
Reaction of suitable substituted olefins with carbon radicals generated from the acyl derivatives of N-hydroxy-2-thiopyridone results in the formation of precursors for the corresponding homo-acids.These compounds can then be transformed to the desired end-products in high yield under mild conditions.
