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1037210-03-9

C40H55NO5 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1037210-03-9 Structure

  • Basic information

    1. Product Name: C40H55NO5
    2. Synonyms: C40H55NO5
    3. CAS NO:1037210-03-9
    4. Molecular Formula:
    5. Molecular Weight: 629.88
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1037210-03-9.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C40H55NO5(CAS DataBase Reference)
    10. NIST Chemistry Reference: C40H55NO5(1037210-03-9)
    11. EPA Substance Registry System: C40H55NO5(1037210-03-9)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1037210-03-9(Hazardous Substances Data)

1037210-03-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1037210-03-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,7,2,1 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1037210-03:
(9*1)+(8*0)+(7*3)+(6*7)+(5*2)+(4*1)+(3*0)+(2*0)+(1*3)=89
89 % 10 = 9
So 1037210-03-9 is a valid CAS Registry Number.

1037210-03-9Relevant articles and documents

Development of a Multi Kilogram-Scale, Tandem Cyclopropanation Ring-Expansion Reaction en Route to Hedgehog Antagonist IPI-926

Austad, Brian C.,Hague, Andrew B.,White, Priscilla,Peluso, Stéphane,Nair, Somarajan J.,Depew, Kristopher M.,Grogan, Michael J.,Charette, André B.,Yu, Lin-Chen,Lory, Caroline D.,Grenier, Louis,Lescarbeau, André,Lane, Benjamin S.,Lombardy, Richard,Behnke, Mark L.,Koney, Nii,Porter, James R.,Campbell, Matthew J.,Shaffer, Jeanne,Xiong, Jimin,Helble, Joseph C.,Foley, Michael A.,Adams, Julian,Castro, Alfredo C.,Tremblay, Martin R.

, p. 786 - 798 (2016)

The formation of the d-homocyclopamine ring system in IPI-926 is the key step in its semisynthesis and proceeds via a chemoselective cyclopropanation followed by a stereoselective acid-catalyzed carbocation rearrangement. In order to perform large-scale cyclopropanation reactions, we developed new iodomethylzinc bis(aryl)phosphate reagents that were found to be both effective and safe. These soluble reagents can be prepared under mild conditions and are stable during the course of the reaction. Importantly, they have favorable energetics relative to other cyclopropanating agents such as EtZnCH2I. Herein, we describe the process optimization studies that led to successful large-scale production of the d-homocyclopamine core necessary for IPI-926.

CYCLOPAMINE ANALOGS

-

Page/Page column 34, (2008/12/07)

The invention provides novel derivatives of cyclopamine having the following formula.

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