103722-00-5

Basic information

• Product Name: (4R,5R)-4-Chloro-5-(2-methoxy-phenyl)-[1,3]oxathiolane 3,3-dioxide
• CAS NO: 103722-00-5
• Molecular Weight: 262.714
• Mol File: 103722-00-5.mol

Chemical Properties

• CAS DataBase Reference: (4R,5R)-4-Chloro-5-(2-methoxy-phenyl)-[1,3]oxathiolane 3,3-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (4R,5R)-4-Chloro-5-(2-methoxy-phenyl)-[1,3]oxathiolane 3,3-dioxide(103722-00-5)
• EPA Substance Registry System: (4R,5R)-4-Chloro-5-(2-methoxy-phenyl)-[1,3]oxathiolane 3,3-dioxide(103722-00-5)

Safety Data

• Hazardous Substances Data: 103722-00-5(Hazardous Substances Data)

Upstream product

• 37557-97-4 bis(chloromethyl)sulfone 
• 135-02-4 ortho-anisaldehyde 

Downstream Products

• 103722-05-0 1-((E)-2-Chloro-vinyl)-2-methoxy-benzene 

Relevant articles and documents

CARBON-CARBON BOND FORMING REACTION OF BIS(CHLOROMETHYL)SULFONE WITH CARBONYL COMPOUNDS: GENERAL ROUTE TO AROMATIC 2-CHLOROVINYL COMPOUNDS AND α-HYDROXYALDEHYDES

Bis(chloromethyl)sulfone (1) has been proved to be a useful reagent for the synthesis of aromatic 2-chlorovinyl compounds (4) from aromatic aldehydes and of α-hydroxyaldehydes (5) from aliphatic carbonyl compounds with one carbon prolongation.The sec-butyllithium-aided reaction of 1 with aromatic aldehydes gives 1,3-oxathiolane-3,3-dioxides (2) which are converted to 4 in good yields by thermolysis.On the other hand, the sodium hydride-aided reaction of 1 with aliphatic carbonyl compounds is favorable to the formation of chloromethylsulfonyloxiranes (3).Titanium tetrachloride has been found to be an efficient reagent for hydrolysis of 3 to 5.