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1037305-43-3

6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 3-({[(2S,6R)-2-[(bis(4-methoxyphenyl)(phenyl)methoxy)methyl]-6-(5-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)morpholin-4-yl](bis(propan-2-yl)amino)phosphanyl}oxy)propanenitrile

    Cas No: 1037305-43-3

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  • 1037305-43-3 Structure

  • Basic information

    1. Product Name: 6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite
    2. Synonyms: 6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite
    3. CAS NO:1037305-43-3
    4. Molecular Formula:
    5. Molecular Weight: 743.84
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1037305-43-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite(CAS DataBase Reference)
    10. NIST Chemistry Reference: 6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite(1037305-43-3)
    11. EPA Substance Registry System: 6'-O-(4,4'-dimethoxytrityl)-3'-O-cyanoethyl-1'-(N1-thymidine) morpholino (N,N-diisopropylamino) phosphorodiamidite(1037305-43-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1037305-43-3(Hazardous Substances Data)

1037305-43-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1037305-43-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,7,3,0 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1037305-43:
(9*1)+(8*0)+(7*3)+(6*7)+(5*3)+(4*0)+(3*5)+(2*4)+(1*3)=113
113 % 10 = 3
So 1037305-43-3 is a valid CAS Registry Number.

1037305-43-3Downstream Products

1037305-43-3Relevant articles and documents

Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras

Langner, Heera K.,Jastrzebska, Katarzyna,Caruthers, Marvin H.

, p. 16240 - 16253 (2020)

This Article outlines the optimized chemical synthesis and preliminary biochemical characterization of a new oligonucleotide analogue called thiophosphoramidate morpholinos (TMOs). Their rational design hinges upon integrating two well-studied pharmacopho

RETRACTED ARTICLE: Synthesis of Phosphorodiamidate Morpholino Oligonucleotides and Their Chimeras Using Phosphoramidite Chemistry

Paul, Sibasish,Caruthers, Marvin H.

, p. 15663 - 15672 (2016)

Phosphorodiamidate morpholinos (PMOs) and PMO-DNA chimeras have been prepared on DNA synthesizers using phosphoramidite chemistry. This was possible by first generating boranephosphoroamidate morpholino internucleotide linkages followed by oxidative subst

Synthesis and properties of morpholino chimeric oligonucleotides

Zhang, Nan,Tan, Chunyan,Cai, Puqin,Jiang, Yuyang,Zhang, Peizhuo,Zhao, Yufen

, p. 3570 - 3573 (2008)

Chimeric oligonucleotides with the novel morpholino modification and the phosphoramidate linkers have been synthesized and characterized. These oligonucleotides showed moderate thermal stability with complementary RNA and DNA, and enhanced resistance towa

SYNTHESIS OF BACKBONE MODIFIED MORPHOLINO OLIGONUCLEOTIDES AND CHIMERAS USING PHOSPHORAMIDITE CHEMISTRY

-

, (2018/04/20)

Amine substituted morpholino oligonucleotides, other than the classical N,N-dimethylamino PMO analogue, and methods of efficiently synthesizing these oligonucleotides with high yield are provided. Morpholino oligonucleotides having thiophosphoramidate, ph

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