10374-23-9

Upstream product

• 3424-93-9 4-methoxyphenylacetamide 
• 100-52-7 benzaldehyde 

Downstream Products

• 1174154-52-9 (R)-N-(1,3-diphenylprop-2-ynyl)-4-methoxybenzamide 
• 25220-25-1 5-(4-methoxyphenyl)-2,4-diphenyloxazole 
• 97015-53-7 2-(4-methoxyphenyl)-4,5-triphenyloxazole 
• 1000681-58-2 4-methoxy-N-((R)-1-phenylbut-3-enyl)benzamide 
• 1163684-18-1 (2R,3S)-2-benzyloxy-3-(4-methoxybenzoyl)amino-3-phenylpropanal 

Relevant academic research and scientific papers

A convenient one-pot approach to Paclitaxel (Taxol) side chain via 1,3-dipolar cycloaddition of carbonyl ylides and N-benzoylbenzyl imines

An efficient cascade approach to α-hydroxy-β-amino acid derivatives is reported, which goes through a 1,3-dipolar cycloaddition of carbonyl ylides and N-benzoylbenzyl imines and followed by hydrolysis under acidic conditions. This is the first example of using N-benzoylbenzyl imine as dipolarophile for 1,3-dipolar cycloaddition with carbonyl ylide, which provides a direct and convenient access for the one-pot synthesis of paclitaxel side chain and its derivatives.