10374-68-2Relevant academic research and scientific papers
Reactivity of α-acylated β-enamino ketones and esters: Synthesis of pyrazoles
Missio, Lauri J.,Braibante, Hugo S.,Braibante, Mara E. F.
, p. 1243 - 1245 (1996)
The reactivity of the enamino compounds 4-amino-3-phenylamino(thio)carbonyl-3-penten-2-one 1 and 2 and ethyl 3-amino-2-phenylamino(thio)carbonyl-2-butyrate 7 and 8 was studied using the reaction with hydrazine hydrate and hydrazine hydrochloride to evaluate the 1,3 electrophilic center of the compounds by the formation of the pyrazole rings. The pyrazoles 3,4,5,9,11 and 13 were obtained depending on the reaction conditions employed.
