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103745-39-7

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Product FOB Price Min.Order Supply Ability Supplier
FASUDIL
Cas No: 103745-39-7
No Data 1000 Gram 10 Metric Ton/Month Hebei yanxi chemical co.,LTD. Contact Supplier
High quality Fasudil Hydrchloride supplier in China
Cas No: 103745-39-7
No Data No Data No Data Simagchem Corporation Contact Supplier
Fasudil
Cas No: 103745-39-7
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
High purity Fasudil with best price and good quality
Cas No: 103745-39-7
No Data 10 Gram 200 Kilogram/Week Hubei Jusheng Technology Co., Ltd., Contact Supplier
TIANFU CHEM--FASUDIL
Cas No: 103745-39-7
No Data 1 Kilogram 100 Kilogram/Month Henan Tianfu Chemical Co., Ltd. Contact Supplier
FASUDIL
Cas No: 103745-39-7
No Data No Data Metric Ton/Day Shijiazhuang Sdyano Fine Chemical Co., Ltd Contact Supplier
High quality Fasudil Hydrchloride supplier in China CAS NO.103745-39-7
Cas No: 103745-39-7
No Data 1 Kilogram 5000 Kilogram/Month Weifang Tansen Yiang international trading co., LTD Contact Supplier
Factory Supply Top Quality FASUDIL
Cas No: 103745-39-7
No Data No Data No Data Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
FASUDIL
Cas No: 103745-39-7
No Data 1 Gram 10 Metric Ton/Month Changzhou Extraordinary Pharmatech co.,LTD Contact Supplier
Fasudil
Cas No: 103745-39-7
No Data 1 Gram No Data Watson International Ltd Contact Supplier

103745-39-7 Usage

Uses

vasodilator (cerebral), Ca antagonist

Biological Activity

Cyclic nucleotide-dependent protein kinase inhibitor and Rho-associated kinase inhibitor (IC50 = 10.7 μM). Ca2+ antagonist and vasodilator. Also inhibits proliferation of vascular smooth muscle cells.

Uses

A potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore A23187 induced co ntraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. Also reported to potently inhibit Rho- associated Kinase (ROCK IC50= 10.7 uM).

Chemical Properties

White Crystalline Solid
InChI:InChI=1/C14H17N3O2S.2ClH/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14;;/h1,3-5,7,11,15H,2,6,8-10H2;2*1H

103745-39-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name FASUDIL

1.2 Other means of identification

Product number -
Other names Fasudilum

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103745-39-7 SDS

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