10375-08-3

Usage

Uses

Used in Personal Care Industry:
N-(3-aminopropyl)dodecanamide is used as an emulsifier and surfactant in the production of shampoos, conditioners, and skin care products for its ability to improve the mixing of oil and water, as well as its conditioning and moisturizing properties.
Used in Textile Industry:
In the textile industry, N-(3-aminopropyl)dodecanamide is used as a softening agent to enhance the texture and feel of fabrics.
Used in Lubricants Industry:
N-(3-aminopropyl)dodecanamide is used as an anti-corrosion additive in lubricants to protect machinery and equipment from corrosion.
Safety Precautions:
It is important to handle N-(3-aminopropyl)dodecanamide with caution and in accordance with safety guidelines due to its potential to cause skin and eye irritation.

InChI:InChI=1/C15H32N2O/c1-2-3-4-5-6-7-8-9-10-12-15(18)17-14-11-13-16/h2-14,16H2,1H3,(H,17,18)

Upstream product

• 111-82-0 methyl n-dodecanoate 
• 109-76-2 Trimethylenediamine 

Relevant academic research and scientific papers

Synthesis and biological evaluation of a new series of N-acyldiamines as potential antibacterial and antifungal agents

In continuation of our efforts to find new antimicrobial compounds, series of fatty N-acyldiamines were prepared from fatty methyl esters and 1,2-ethylenediamine, 1,3-propanediamine or 1,4-butanediamine. The synthesized compounds were screened for their antibacterial activity against Gram-positive bacteria (Staphylococcus aureus, Staphylococcus epidermidis), Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and for their antifungal activity against four species of Candida (C. albicans, C. tropicalis, C. glabrata and C. parapsilosis). Compounds 5a (N-(2-aminoethyl)dodecanamide), 5b (N-(2-aminoethyl)tetracanamide) and 6d (N-(3-aminopropyl)oleamide) were the most active against Gram-positive bacteria, with MIC values ranging from 1 to 16 μg/mL and were evaluated for their activity against 21 clinical isolates of methicillin-resistant S. aureus. All the compounds exhibited good to moderate antifungal activity. Compared to chloramphenicol, compound 6b displayed a similar activity (MIC50= 16 μg/mL). A positive correlation could be established between lipophilicity and biological activity.