10375-08-3

Basic information

• Product Name: N-(3-aminopropyl)dodecanamide
• Synonyms: N-(3-aminopropyl)dodecanamide;Dodecanamide, N-(3-aminopropyl)-;Dodecanoic acid, 1,3-propylenediamine monoamide;Einecs 233-817-8
• CAS NO: 10375-08-3
• Molecular Formula: C15H32N2O
• Molecular Weight: 256.42738
• EINECS: 233-817-8
• Mol File: 10375-08-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 414.6°C at 760 mmHg
• Flash Point: 204.6°C
• Appearance: /
• Density: 0.897g/cm³
• Vapor Pressure: 4.38E-07mmHg at 25°C
• Refractive Index: 1.462
• CAS DataBase Reference: N-(3-aminopropyl)dodecanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-aminopropyl)dodecanamide(10375-08-3)
• EPA Substance Registry System: N-(3-aminopropyl)dodecanamide(10375-08-3)

Safety Data

• Hazardous Substances Data: 10375-08-3(Hazardous Substances Data)

Usage

General Description

N-(3-aminopropyl)dodecanamide, also known as lauroyl ethylenediamine, is a chemical compound with the molecular formula C15H32N2O. It is an amide derivative of dodecanoic acid and ethylenediamine, and is commonly used as an emulsifier and surfactant in various industrial and personal care products. N-(3-aminopropyl)dodecanamide is often utilized in the production of shampoos, conditioners, and skin care products due to its ability to improve the mixing of oil and water, as well as its conditioning and moisturizing properties. Additionally, it has applications in the textile industry as a softening agent and in lubricants as an anti-corrosion additive. However, it is important to handle N-(3-aminopropyl)dodecanamide with caution and in accordance with safety guidelines due to its potential to cause skin and eye irritation.

InChI:InChI=1/C15H32N2O/c1-2-3-4-5-6-7-8-9-10-12-15(18)17-14-11-13-16/h2-14,16H2,1H3,(H,17,18)

Upstream product

• 111-82-0 methyl n-dodecanoate 
• 109-76-2 Trimethylenediamine 

Relevant articles and documents

Synthesis and biological evaluation of a new series of N-acyldiamines as potential antibacterial and antifungal agents

In continuation of our efforts to find new antimicrobial compounds, series of fatty N-acyldiamines were prepared from fatty methyl esters and 1,2-ethylenediamine, 1,3-propanediamine or 1,4-butanediamine. The synthesized compounds were screened for their antibacterial activity against Gram-positive bacteria (Staphylococcus aureus, Staphylococcus epidermidis), Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and for their antifungal activity against four species of Candida (C. albicans, C. tropicalis, C. glabrata and C. parapsilosis). Compounds 5a (N-(2-aminoethyl)dodecanamide), 5b (N-(2-aminoethyl)tetracanamide) and 6d (N-(3-aminopropyl)oleamide) were the most active against Gram-positive bacteria, with MIC values ranging from 1 to 16 μg/mL and were evaluated for their activity against 21 clinical isolates of methicillin-resistant S. aureus. All the compounds exhibited good to moderate antifungal activity. Compared to chloramphenicol, compound 6b displayed a similar activity (MIC50= 16 μg/mL). A positive correlation could be established between lipophilicity and biological activity.