103755-46-0 Usage
Chemical Class
Acetamides
Contains an indazole ring
Provides potential for diverse interactions with biological targets
Used in research and pharmaceutical applications
Due to potential pharmacological properties
Biological activities
Antiviral, anticancer, and antibacterial properties
Interaction with biological systems
Potential to act as a pharmaceutical agent
Promising candidate for further study and drug development
Due to its diverse range of interactions and potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 103755-46-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,5 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 103755-46:
(8*1)+(7*0)+(6*3)+(5*7)+(4*5)+(3*5)+(2*4)+(1*6)=110
110 % 10 = 0
So 103755-46-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H9N3O/c10-9(13)5-8-6-3-1-2-4-7(6)11-12-8/h1-4H,5H2,(H2,10,13)(H,11,12)
103755-46-0Relevant articles and documents
Novel indolylindazolylmaleimides as inhibitors of protein kinase C-β: Synthesis, biological activity, and cardiovascular safety
Zhang, Han-Cheng,Derian, Claudia K.,McComsey, David F.,White, Kimberly B.,Ye, Hong,Hecker, Leonard R.,Li, Jian,Addo, Michael F.,Croll, Diane,Eckardt, Annette J.,Smith, Charles E.,Li, Quan,Cheung, Wai-Man,Conway, Bruce R.,Emanuel, Stuart,Demarest, Keith T.,Andrade-Gordon, Patricia,Damiano, Bruce P.,Maryanoff, Bruce E.
, p. 1725 - 1728 (2005)
Novel indolylindazolylmaleimides were synthesized and examined for kinase inhibition. We identified low-nanomolar inhibitors of PKC-β with good to excellent selectivity vs other PKC isozymes and GSK-3β. In a cell-based functional assay, 8f and 8i effectiv
