103765-60-2

Basic information

• Product Name: 2-(N-methyl-N-phenylamino)-4-phenylthiazole
• Synonyms: 2-(N-methyl-N-phenylamino)-4-phenylthiazole
• CAS NO: 103765-60-2
• Molecular Weight: 266.367
• Mol File: 103765-60-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(N-methyl-N-phenylamino)-4-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-methyl-N-phenylamino)-4-phenylthiazole(103765-60-2)
• EPA Substance Registry System: 2-(N-methyl-N-phenylamino)-4-phenylthiazole(103765-60-2)

Safety Data

• Hazardous Substances Data: 103765-60-2(Hazardous Substances Data)

Upstream product

• 4104-75-0 1-methyl-1-phenylthiourea 
• 98-86-2 acetophenone 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 118134-29-5 5-deutero-2-(N-methylanilino)-4-phenylthiazole 
• 111753-03-8 1-{2-[N-methyl(phenyl)amino]-4-phenyl-1,3-thiazol-5-yl}ethanone 

Relevant articles and documents

Carbon tetrabromide mediated oxidative cyclocondensation of ketones and thioureas: An easy access to 2-aminothiazoles

A simple, mild, and efficient one-pot method for the synthesis of substituted 2-aminothiazoles has been reported. The reaction involves the formation of sulfenyl bromide as an umpolung intermediate of nucleophilic sulfur, which is responsible for C-S bond formation leading to oxidative cyclization of ketones and thioureas to furnish the desired products. Carbon tetrabromide was used as a convenient and mild brominating reagent under basic condition at room temperature to give 2-aminothiazoles in good to excellent yields.