103767-37-9Relevant academic research and scientific papers
Synthesis and anticancer activities of amphiphilic 5-fluoro-2′- deoxyuridylic acid prodrugs
Ludwig, Peter S.,Schwendener, Reto A.,Schott, Herbert
, p. 494 - 504 (2007/10/03)
Amphiphilic anticancer prodrugs of 5′-fluoro-2′-deoxyuridine- 5′-monophosphate (5-FdUMP) were synthesized according to the hydrogen phosphonate method by coupling lipophilic cytosine derivatives or a phospholipid with 5-fluoro-2′-deoxyuridine (5-FdU). Stu
Synthesis and biological activity of aromatic amino acid phosphoramidates of 5-fluoro-2'-deoxyuridine and 1-β- arabinofuranosylcytosine: Evidence of phosphoramidase activity
Abraham, Timothy W.,Kalman, Thomas I.,McIntee, Edward J.,Wagner, Carston R.
, p. 4569 - 4575 (2007/10/03)
The amino acid phosphoramidate diesters of FUdR (2) and Ara-C (6), 5- fluoro-2'-deoxy-5'-uridyl N-(1-carbomethoxy-2-phenylethyl)phosphoramidate (5a), 5-fiuoro-2'-deoxy-5'-uridyl N-(1-carbomethoxy-2- indolylethyl)phosphoramidate (5b), 1-β-arabinofuranosylc
