103772-40-3

Basic information

• Product Name: H-D-HIS(BZL)-OH
• Synonyms: N-IM-BENZYL-D-HISTIDINE;H-D-HIS(BZL)-OH;D-HISTIDINE(BZL)-OH;D-His(Bzl)-OH
• CAS NO: 103772-40-3
• Molecular Formula: C13H15N3O2
• Molecular Weight: 245.28
• Mol File: 103772-40-3.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: H-D-HIS(BZL)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-D-HIS(BZL)-OH(103772-40-3)
• EPA Substance Registry System: H-D-HIS(BZL)-OH(103772-40-3)

Safety Data

• Hazardous Substances Data: 103772-40-3(Hazardous Substances Data)

Usage

General Description

"H-D-HIS(BZL)-OH" is a chemical compound that consists of a dipeptide containing the amino acids histidine and benzoyl aspartic acid. H-D-HIS(BZL)-OH is commonly used in research and pharmaceutical applications due to its ability to mimic natural peptides and interact with specific receptors in the body. The benzoyl group attached to the histidine residue increases the compound's stability and solubility, making it a valuable tool in drug development and peptide synthesis. "H-D-HIS(BZL)-OH" has shown promise in various studies for its potential therapeutic effects in treating conditions such as cancer, inflammation, and neurodegenerative diseases.

Upstream product

• 20898-44-6 Boc-His(Bzl)-OH 
• 100-44-7 benzyl chloride 
• 71-00-1 L-histidine 
• 71-00-1 L-histidine 

Downstream Products

• 96216-64-7 1-benzyl-N^α-[4-(4-methoxy-phenylazo)-benzyloxycarbonyl]-histidine 
• 21929-66-8 N^α-carbobenzoxy-N^im-benzyl-L-histidine 
• 909278-46-2 1-benzyl-N^α-(toluene-4-sulfonyl)-L-histidine 
• 93983-56-3 τ-benzyl-L-histidine methyl ester dihydrochloride 
• 133868-67-4 1-benzyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid methyl ester 
• 1300034-13-2 1-benzyl-1H-imidazo[4,5-c]pyridin-6-carboxylic acid methyl ester 
• 19817-75-5 N'-benzyl-L-histidine methyl ester 
• 122766-72-7 1-benzyl-N^α-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-L-histidine-benzyl ester 
• 122411-85-2 1benzyl-N^α-(N-benzyloxycarbonyl-L-phenylalanyl)-L-histidine-hydrazide 
• 120548-57-4 N-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-glycine-benzyl ester 
• 105374-43-4 N-(1-benzyl-N^α-benzyloxycarbonyl-L-histidyl)-glycine 
• 104882-34-0 1-benzyl-N^α-methyl-N^α-(toluene-4-sulfonyl)-L-histidine 
• 98189-03-8 N,N-dihexadecyl-N^α_his-α_ala-(t-butoxycarbonyl)-L-alanyl>-N^im-benzyl-L-histidinamide 
• 98189-06-1 N,N-dihexadecyl-N^α_his-Α_ala-(6-bromohexanoyl)-L-alanyl>-N^im-benzyl-L-histidinamide 

Relevant articles and documents

PROCESS FOR SYNTHESIZING ERGOTHIONEINE AND RELATED COMPOUNDS

The invention provides a process for synthesising a compound of formula (V) wherein: formula (z) or a physiologically acceptable salt, tautomer, stereoisomer or mixture of stereoisomers thereof. The process utilizes a /V-benzyl protected histidine rather

Regiospecific alkylation of histidine and histamine at N-1 (τ)

Series of 1-alkyl histidines and histamines have been synthesized by the alkylation of the corresponding 5,6,7,8-tetrahydro-5-oxomidazo[1,5-c]pyrimidines with alkyl halides in aprotic solvents. The method of conversion of the intermediate quaternary salt to the amino acid or amino depends on the nature of the alkyl group.

CYCLIC CARBAMATE ANALOGUES OF (+)-PILOCARPINE

Pilocarpine analogues are provided having the structure STR1 where one of R 1 or R 2 is an alkyl, such as methyl, ethyl, propyl, butyl, and so forth, and the corresponding secondary alkyl groups, an aralkyl, such as benzyl, phenylethyl, phenylpropyl, and the corresponding secondary aralkyl residues, or a cycloalkyl having less than about 12 carbon atoms. R 3 has at least two carbon atoms but less than about 9. These pilocarpine analogues have improved duration of biological activity with respect to pilocarpine. A particularly preferred compound is a muscarinic agonist equipotent with pilocarpine, where R 2 is methyl, and R 3 is ethyl.