1037763-75-9

Upstream product

• 196799-45-8 2,3-dihydrobenzofuran-7-carbaldehyde 
• 35700-40-4 2,3-dihydrobenzofuran-7-carboxylic acid 
• 1037763-65-7 N-methoxy-N-methyl-2,3-dihydrobenzofuran-7-carboxamide 
• 1037763-70-4 methyl 8-iodo-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylate 
• 327183-73-3 methyl 3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylate 
• 1037763-72-6 methyl 8-(2-methoxypyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxylate 
• 85117-99-3 2-(bromomethyl)-1,4-difluorobenzene 

Downstream Products

• 1037763-77-1 6-(2,5-difluorobenzyl)-8-(2-methoxypyridin-3-yl)-3,6-dihydro-2H-1-oxa-6-azaasindacene-7-carboxylic acid 
• 1037763-79-3 6-(2,5-difluorobenzyl)-8-(2-methoxypyridin-3-yl)-N-(methylsulfonyl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxamide 
• 1037758-74-9 6-(2,5-difluorobenzyl)-N-(methylsulfonyl)-8-(2-oxo-1,2-dihydropyridin-3-yl)-3,6-dihydro-2H-furo[2,3-e]indole-7-carboxamide 

Relevant academic research and scientific papers

Synthesis of new 4,5-dihydrofuranoindoles and their evaluation as HCV NS5B polymerase inhibitors

The synthesis of substituted 3,4-dihydrofuranoindoles is reported. These new indole compounds were used to synthesize potent HCV NS5B inhibitors. The binding mode of the dihydrofuranoindole-derived inhibitors was established via X-ray crystallographic stu

4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS

The present invention relates to 4,5-ring annulated indole derivatives, compositions comprising at least one 4,5-ring annulated indole derivatives, and methods of using the 4,5-ring annulated indole derivatives for treating or preventing a viral infection or a virus-related disorder in a patient. Wherein ring Z, of formula (I), is a cyclopentyl, cyclopentenyl, 5-membered heterocycloalkyl, 5-membered heterocycloalkenyl or 5-membered heteroaryl ring.