103777-45-3

Upstream product

• 108-95-2 phenol 
• 118-79-6 2,4,6-tribromophenol 
• 20491-92-3 2,4,6-trimethoxyphenol 
• 108-24-7 acetic anhydride 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 

Downstream Products

• 105905-65-5 1-(3-chloro-2,4,6-trimethoxy-phenyl)-ethanone 
• 119892-40-9 6-hydroxy-5,7-dimethoxyflavone 
• 491-67-8 5,6,7-trihydroxy-2-phenyl-4H-1-benzopyran-4-one 
• 103777-59-9 3,4-Bis-benzyloxy-benzoic acid 2-acetyl-6-dodecyloxy-3,5-dimethoxy-phenyl ester 
• 103777-08-8 5-(dodecyloxy)-6-hydroxy-2,4-dimethoxy-ω-<3,4-bis(benzyloxy)benzoyl>acetophenone 
• 103777-32-8 3',4'-bis(benzyloxy)-8-(dodecyloxy)-5,7-dimethoxyflavone 
• 103776-79-0 8-(dodecyloxy)-3',4'-dihydroxy-5,7-dimethoxyflavone 
• 103777-47-5 5-(dodecyloxy)-6-hydroxy-2,4-dimethoxyacetophenone 
• 102508-38-3 8-(dodecyloxy)-3',4',5-trihydroxy-7-methoxyflavone 
• 103777-46-4 1-(3-Dodecyloxy-2,4,6-trimethoxy-phenyl)-ethanone 

Relevant academic research and scientific papers

Method for preparing baicalein

The invention relates to a method for preparing anti-virus and anti-bacterial inflammatory medicine baicalein. According to the method, phenol serves as a starting material, and a key chalcone intermediate is prepared through bromination, methoxy substitution, Friedel-crafts acylation and aldol condensation; the key intermediate is subjected to oxidative cyclisation and methyl removal reaction, and high-purity baicalein can be prepared. According to the new method, adopted raw reagents are cheap and easy to obtain, the number of synthesis steps is small, reaction operation is easy and convenient, production control is easy, the product yield is high, purity is good, and the method is suitable for production and application of baicalein.

A new method for halogenation of aromatic compounds by using dimethyldioxirane and tetrabutylammonium halides

In this presentation the novel regioselective halogenation of arenes or phenols with dimethyldioxirane and Bu4NX is described. The results showed that a new, versatile and mild method can be utilized for preparation of aryl halides starting with arenes or phenols. Finally, this aryl halide forming methodology is applicable to structurally more complex flavonoids.