103788-07-4 Usage
Uses
Used in Pharmaceutical Industry:
2,4-Thiazolidinedione, 5-[[4-[2-[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]ethoxy]phenyl]methyl]is used as a pharmaceutical candidate for various applications due to its diverse biological activities. Its unique structure allows it to interact with different biological targets, making it a promising compound for the development of new drugs.
Used in Drug Discovery:
2,4-Thiazolidinedione, 5-[[4-[2-[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]ethoxy]phenyl]methyl]is used in drug discovery as a starting point for the development of new therapeutic agents. Its complex molecular structure provides opportunities for optimization and modification to enhance its biological activity and selectivity.
Used in Medicinal Chemistry Research:
2,4-Thiazolidinedione, 5-[[4-[2-[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]ethoxy]phenyl]methyl]is utilized in medicinal chemistry research to study its structure-activity relationships and to understand the underlying mechanisms of its biological activities. This knowledge can be applied to design and develop more effective and targeted therapeutic agents.
Note: The specific applications and industries mentioned above are hypothetical and provided as examples based on the general properties of thiazolidinedione compounds. Further research and development are needed to determine the exact uses and potential of 2,4-Thiazolidinedione, 5-[[4-[2-[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]ethoxy]phenyl]methyl]-.
Check Digit Verification of cas no
The CAS Registry Mumber 103788-07-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,8 and 8 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 103788-07:
(8*1)+(7*0)+(6*3)+(5*7)+(4*8)+(3*8)+(2*0)+(1*7)=124
124 % 10 = 4
So 103788-07-4 is a valid CAS Registry Number.
103788-07-4Relevant academic research and scientific papers
Studies on antidiabetic agents. 11. Novel thiazolidinedione derivatives as potent hypoglycemic and hypolipidemic agents
Sohda,Mizuno,Momose,Ikeda,Fujita,Meguro
, p. 2617 - 2626 (2007/10/02)
In the course of further chemical modification of the novel antidiabetic pioglitazone (AD-4833, U-72, 107), a series of 5-[4-(2- or 4- azolylalkoxy)benzyl- or -benzylidene]-2,4-thiazolidinediones was prepared and evaluated for hypoglycemic and hypolipidemic activities in insulin-resistant, genetically obese, and diabetic KKA(y) mice. Replacement of the 2-pyridyl moiety of pioglitazone by a 2- or 4-oxazolyl or a 2- or 4-thiazolyl moiety greatly enhanced in vivo potency. The corresponding 5-benzylidene-type compounds, in which a methine was used as a linker between the benzene ring and the thiazolidinedione ring, also had potent biological activity. Among the compounds synthesized, 5-[4-[2-(5-methyl-2-phenyl-4- oxazolyl)ethoxy]benzyl]-2,4-thiazolidinedione (18) exhibited the most potent activity, more than 100 times that of pioglitazone. The synthesis and structure-activity relationships for this novel series of derivatives are detailed.
