1038-28-4

Usage

Uses

Used in Pharmaceutical Research:
Gona-2,5(10)-dien-17-ol,13-ethyl-3-methoxy-, (17b)-(?à)(9CI) is used as a potential treatment for various conditions such as muscle wasting and hormone deficiency. Its chemical properties and testosterone-like structure make it a promising candidate for addressing these health issues.
Used in Hormone Replacement Therapy:
In the field of endocrinology, Gona-2,5(10)-dien-17-ol,13-ethyl-3-methoxy-, (17b)-(?à)(9CI) is being studied for its potential use in hormone replacement therapy for men. Its ability to mimic the effects of testosterone may help alleviate symptoms associated with hormone deficiency.
Used as a Performance-Enhancing Drug:
Although its use and distribution are regulated, Gona-2,5(10)-dien-17-ol,13-ethyl-3-methoxy-, (17b)-(?à)(9CI) is being studied for its potential as a performance-enhancing drug. Its anabolic and androgenic properties may provide athletes and bodybuilders with increased muscle mass and strength.
Used in the Synthesis of Other Steroid Compounds:
Gona-2,5(10)-dien-17-ol,13-ethyl-3-methoxy-, (17b)-(?à)(9CI) is also utilized in the synthesis of other steroid compounds. Its unique chemical structure allows for the creation of new compounds with potential applications in various industries.
Used in Sports and Bodybuilding:
While its use in sports and bodybuilding is regulated due to its potential for abuse and misuse, Gona-2,5(10)-dien-17-ol,13-ethyl-3-methoxy-, (17b)-(?à)(9CI) is still being studied for its potential benefits in these fields. Its ability to enhance performance and increase muscle mass makes it a compound of interest for athletes and bodybuilders seeking to improve their physical capabilities.

Upstream product

• 101025-90-5 Acetic acid 2-ethyl-3-vinyl-cyclopent-1-enyl ester 
• 75863-25-1 2-Trimethylsilyl-1-(4-methoxy-2-methylphenyl)prop-2-en-1-on 
• 848-05-5 (+/-)-13-Ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,9⁽¹¹⁾-tetraen-17-on 

Downstream Products

• 797-63-7 norgestrel 
• 797-58-0 DL-17β-Hydroxy-13β.17α-diethyl-gon-4-en-3-on 
• 848-04-4 dl-13-ethyl-3-ethoxygona-1,3,5⁽¹⁰⁾-trien-17-one 
• 2322-77-2 dl-3-methoxy-13β-ethylgona-2,5(10)-dien-17-one 

Relevant academic research and scientific papers

Total synthesis with a chirogenic opening move demonstrated on steroids with estrane or 18a-homoestrane skeleton

A concept of first choice for the synthesis of the title compounds had been proposed by Dane in the late 1930s. It was soon turned down, because the opening move - a chirogenic Diels-Alder reaction - did not work. With Lewis acids as mediators, however, a successful start has been achieved now. With Ti complexes of chelating ligands (Seebach's TADDOLs (= α,α,α',α'-tetraaryl-1,3-dioxolane-4,5-dimethanols)), enantioselective formation of the desired adducts does occur. Efficient total syntheses of 2 and 3a have been accomplished.

Synthesis of 13-alkyl-gon-4-ones

The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.