103810-85-1Relevant articles and documents
Catalyst-Free Transamidation of Aromatic Amines with Formamide Derivatives and Tertiary Amides with Aliphatic Amines
Yin, Jiawen,Zhang, Jingyu,Cai, Changqun,Deng, Guo-Jun,Gong, Hang
supporting information, p. 387 - 392 (2019/01/11)
A simple catalyst- and promoter-free protocol has been developed for the transamidation of weakly nucleophilic aromatic amines with formamide derivatives and low-reactivity tertiary amides with aliphatic amines. This strategy is advantageous because no catalyst or promoters are needed, no additives are required, separation and purification is easy, and the reaction is scalable. Significantly, this strategy was further applied to synthesize several pharmaceutical molecules on a gram scale, and excellent yields were achieved.
Polyene compounds useful in the treatment of allergic responses
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, (2008/06/13)
Polyene compounds represented by the general formula STR1 where R=H or lower alkyl group of from 1 to 5 carbon atoms STR2 n is 0-1 x is O or S; and R1 =an alkyl group of from 1 to 5 carbon atoms; and the pharmaceutically acceptable salts thereo
