103816-91-7Relevant academic research and scientific papers
Stereocontrolled double functionalization of (cyclohexadiene)- and (cycloheptadiene)iron complexes via oxidative cyclization techniques
Pearson, Anthony J.,Kole, Sandra L.,Yoon, Jaeyon
, p. 2075 - 2081 (2008/10/08)
Oxidative cyclization of primary alcohol groups onto diene-Fe(CO)2L systems in six- and seven-membered rings has been investigated by using a variety of oxidizing agents and various substituents on the diene. The product cyclic ethers, e.g., complexes 6,17, and 18, are readily opened on treatment with tetrafluoroboric acid in the presence of acetic anhydride to give stereospecifically substituted dienyl-Fe(CO)2L complexes 7 and 16. Nucleophilic addition to these latter complexes occurs stereo- and regiospecifically, allowing access to cis 1,2-disubstitution in the six-membered ring and cis 1,3-disubstitution in the seven-membered ring.
