103818-66-2

Basic information

• Product Name: methyl N-cyclohexyl-3-phenylpropanimidate
• CAS NO: 103818-66-2
• Molecular Weight: 245.365
• Mol File: 103818-66-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl N-cyclohexyl-3-phenylpropanimidate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-cyclohexyl-3-phenylpropanimidate(103818-66-2)
• EPA Substance Registry System: methyl N-cyclohexyl-3-phenylpropanimidate(103818-66-2)

Safety Data

• Hazardous Substances Data: 103818-66-2(Hazardous Substances Data)

Upstream product

• 108-91-8 cyclohexylamine 
• 124-41-4 sodium methylate 
• 87207-67-8 (1-chloro-1-phenyl-2-propylidene)cyclohexylamine 

Relevant articles and documents

The Favorskii Rearrangement of α-Chloro Ketimines

The Favorskii rearrangement of α-chloro ketimines has been studied.It was shown that the base-induced rearrangement of α-chloro ketimines afforded imidates or amides via a mechanism involving 1,3-dehydrochlorination and ring-opening of the resulting cyclopropylideneamines.The ring-opening occurred in such a way as to produce the most stable carbanion.The entire mechanism paralleled the well-known cyclopropanone mechanism of the Favorskii rearrangement of the corresponding oxygen analogues, i.e., α-halo ketones.Evidence has been presented that the semibenzilic-type mechanism is not operative in the cases studied.Depending upon the reaction conditions and the substrate, the Favorskii rearrangement was accompanied by various side reactions including nucleophilic substitution, 1,2-dehydrochlorination, rearrangement via intermediate α-alkoxyaziridines, and self-condensation.