1038342-87-8

Upstream product

• 1397833-65-6 (2-amino-4-chlorophenyl) (benzotriazole-1-yl)methanone 
• 67-63-0 isopropyl alcohol 
• 89-77-0 2-Amino-4-chlorobenzoic acid 

Downstream Products

• 1038343-22-4 C₁₇H₁₅Cl₂NO₃ 
• 1038343-21-3 C₁₇H₁₅ClFNO₃ 
• 1038343-23-5 C₁₇H₁₄ClF₂NO₃ 

Relevant academic research and scientific papers

A simple, mild, and practical method for the esterification and thioesterification of anthranilic acid utilizing N -(2-Aminobenzoyl) benzotriazole

A convenient and efficient method for the preparation of anthranilic esters and anthranilic thioesters has been developed by the treatment of N-(2-aminobenzoyl)benzotriazoles with alcohols and thiols in the presence of 4-(dimethylamino)pyridine (DMAP).

Synthesis and anti-platelet evaluation of 2-benzoylaminobenzoate analogs

Fifty-two 2-benzoylaminobenzoate analogs were synthesized and subjected to anti-platelet aggregation assay using arachidonic acid (AA), collagen (Col), thrombin (Thr), and U46619 as inducers. The results revealed that most of 2-benzoylaminobenzoic acid derivatives showed a selectively inhibitory effect on AA-induced platelet aggregation. As a result of the 2-benzoylaminobenzoic acid derivatives (18, 44, and 46), there were no inhibitory effects on platelet aggregation induced by U46619, but these elicited an inhibitory effect on thromboxane B2 formation at 1.0 μM. These 2-benzoylaminobenzoate analogs were therefore proposed as cyclooxygenase inhibitors.