103841-64-1

Upstream product

• 501-53-1 benzyl chloroformate 
• 57471-70-2 diethyl N-benzyloxycarbonyl-(S)-aspartate 
• 13552-87-9 L-aspartic acid diethyl ester 

Downstream Products

• 25070-76-2 benzyl diallylcarbamate 
• 1359874-78-4 5-[[[1-(tert-butoxycarbonylaminomethyl)-2-ethoxycarbonyl-ethyl]benzyloxycarbonylamino]methyl]-4,5-dihydro-isoxazole-3-carboxylic acid ethyl ester 
• 1359874-77-3 (S)-3-[(N-allyl)benzyloxycarbonylamino]-4-tert-butoxycarbonylamino-butyric acid ethyl ester 
• 1359874-76-2 (S)-3-[(N-allyl)benzyloxycarbonylamino]-4-azidobutyric acid ethyl ester 
• 103841-66-3 ethyl (S)-3-benzylamino-4-2'-tetrahydropyranoxybutyrate 
• 103841-65-2 ethyl (S)-3-N-benzyloxycarbonylamino-4-2'-tetrahydropyranoxybutyrate 

Relevant academic research and scientific papers

Studies towards the total synthesis of batzelladine A

Application of a diastereoselective three-component coupling to the bicyclic core of the batzelladine alkaloids is described. The synthesis features the elaboration of glutamic acid by use of Eschenmoser sulfide contraction. An earlier approach is also included, which shows some limitations of dithiane chemistry when applied to the particular compounds required for this target.

NOVEL BETA-LACTAM COMPOUNDS AND PROECSS FOR PRODUCING THE SAME

1. A β-lactam compound of the formula [1]; ???wherein R1 is a lower alkyl, a lower alkyl substituted by a hydroxy; R2 is a hydrogen, a lower alkyl; X is O, S, NH; m and n are 0 to 4, Y1 is a halogen, cyano, a hydroxy, an amino, a lower alkyloxy, a lower alkylamino, a carboxy, a carbamoyl, a lower alkyl, etc., Y2 is hydrogen, an alkyl, cyano, -C(R3)=NR4 (wherein R3 and R4 are hydrogen, an amino, an alkyl, etc., or R3 and R4 may combine each other together with the nitrogen atom to form a 5- to 7-membered heterocyclic group), or a pharmaceutically acceptable salt thereof, or a non-toxic ester thereof, which has an excellent antibacterial activity against Gram-positive bacteria, especially against MRSA and MRCNS.