57471-70-2Relevant academic research and scientific papers
Novel pyridinium-type fullerene derivatives as multitargeting inhibitors of HIV-1 reverse transcriptase, HIV-1 protease, and HCV NS5B polymerase
Kobayashi, Toi,Mashino, Tadahiko,Nakamura, Shigeo,Ohe, Tomoyuki,Takahashi, Kyoko,Yasuno, Takumi
supporting information, (2021/08/12)
In the present study, we newly synthesized four types of novel fullerene derivatives: pyridinium/ethyl ester-type derivatives 3b?3l, pyridinium/carboxylic acid-type derivatives 4a, 4e, 4f, pyridinium/amide-type derivative 5a, and pyridinium/2-morpholinone
A concise [C+NC+CC] coupling-enabled synthesis of kaitocephalin
Garner, Philip,Weerasinghe, Laksiri,Van Houten, Ian,Hu, Jieyu
, p. 4908 - 4910 (2014/05/06)
A 15-step synthesis of the iGluR antagonist kaitocephalin from aspartic acid is reported. The linchpin pyrrolidine ring of the target molecule is efficiently assembled with in a single operation via an asymmetric [C+NC+CC] reaction.
Studies towards the total synthesis of batzelladine A
Elliott, Mark C.,Long, Matthew S.
, p. 2003 - 2011 (2007/10/03)
Application of a diastereoselective three-component coupling to the bicyclic core of the batzelladine alkaloids is described. The synthesis features the elaboration of glutamic acid by use of Eschenmoser sulfide contraction. An earlier approach is also included, which shows some limitations of dithiane chemistry when applied to the particular compounds required for this target.
