103841-89-0Relevant academic research and scientific papers
A New Synthesis of β-Lactams via Photochemical γ-Hydrogen Abstraction of Monothioimides
Sakamoto, Masami,Watanabe, Shoji,Fujita, Tsutomu,Tohnishi, Masakazu,Aoyama, Hiromu,Omote, Yoshimori
, p. 2203 - 2208 (2007/10/02)
Photochemical reactions of acyclic and semicyclic monothioimides were studied.Photolysis of acyclic monothioimides gave β-lactams (Type II cyclization products) and thioamides (Type II cleavage products). 4-Mercapto-β-lactams were isolated as 4-acylthio-β-lactams by acylation with benzoyl chloride or acetyl chloride in the presence of triethylamine.Irradation of six- or seven- membered semicyclic monothioimides gave bicyclic β-lactams, but five-membered semicyclic monothioimides gave only Type II cleavage products.
