1038502-72-5

Basic information

• Product Name: 1-tosyl-4-vinyl-1,4-dihydro-2H-benzo[d] [1,3]oxazin-2-one
• Synonyms: 1-tosyl-4-vinyl-1,4-dihydro-2H-benzo[d] [1,3]oxazin-2-one
• CAS NO: 1038502-72-5
• Molecular Weight: 329.376
• Mol File: 1038502-72-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-tosyl-4-vinyl-1,4-dihydro-2H-benzo[d] [1,3]oxazin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tosyl-4-vinyl-1,4-dihydro-2H-benzo[d] [1,3]oxazin-2-one(1038502-72-5)
• EPA Substance Registry System: 1-tosyl-4-vinyl-1,4-dihydro-2H-benzo[d] [1,3]oxazin-2-one(1038502-72-5)

Safety Data

• Hazardous Substances Data: 1038502-72-5(Hazardous Substances Data)

Upstream product

• 50609-24-0 ethyl (2-formylphenyl)carbamate 
• 42250-17-9 ethyl N-[2-(hydroxymethyl)phenyl]carbamate 
• 164226-32-8 2-(tert-butyloxycarbonyl)aminobenzyl alcohol 
• 118-92-3 anthranilic acid 
• 5344-90-1 2-Aminobenzyl alcohol 
• 117550-36-4 methyl ortho-(hydroxymethyl)phenyl carbamate 
• 160354-69-8 2-(methyloxycarbonyl)aminobenzaldehyde 
• 899438-69-8 3-(2-oxopropyl)-4-vinyl-3,4-dihydroquinolin-2(1H)-one 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1174333-11-9 4-methyl-N-(2-(1-(pyrrolidin-1-yl)allyl)phenyl)benzenesulfonamide 
• 1174333-12-0 4-methyl-N-(2-(1-(piperidin-1-yl)allyl)phenyl)benzenesulfonamide 
• 13268-54-7 1-tosyl-1, 2-dihydroquinoline 
• 1174333-15-3 (E)-4-methyl-N-(3-(2-(4-methylphenylsulfonamido)phenyl)allyl)-N-phenylbenzenesulfonamide 
• 1174333-10-8 C₂₄H₂₂N₂O₅S₂ 
• 1174333-14-2 C₂₄H₂₆N₂O₂S 
• 1174333-13-1 N-(2-(1-(benzylamino)allyl)phenyl)-4-methylbenzenesulfonamide 

Relevant articles and documents

Access to 5,6-Spirocycles Bearing Three Contiguous Stereocenters via Pd-Catalyzed Stereoselective [4 + 2] Cycloaddition of Azadienes

We present herein a highly diastereo- and enantioselective Pd-catalyzed [4 + 2] cycloaddition of benzofuran-derived azadienes with vinyl benzoxazinanones, which represents a rare highly stereoselective cycloaddition of this class of fused azadienes as a two-atom synthon. The use of a phosphoramidite ligand bearing a chiral secondary amine with a simple biphenyl backbone proved to be the key to construct the novel spirocyclic tetrahydroquinoline scaffold containing three contiguous stereocenters as a single diastereomer in high enantioselectivity.

Enantioselective Construction of Tetrahydroquinazoline Motifs via Palladium-Catalyzed [4 + 2] Cycloaddition of Vinyl Benzoxazinones with Sulfamate-Derived Cyclic Imines

A palladium-catalyzed enantioselective [4 + 2] cycloaddition reaction of vinyl benzoxazinones with sulfamate-derived cyclic imines is described, affording the tetrahydroquinazolines bearing several functional rings in high yields (up to 99% yield) with good to excellent diastereoselectivities and excellent enantioselectivities (up to 96% ee). This reaction represents the first Pd-catalyzed asymmetric decarboxylative cycloaddition of vinyl benzoxazinones with imines.