103854-74-6

Basic information

• Product Name: 1-(4-METHYLBENZYL)-2-THIOUREA
• Synonyms: 1-(4-METHYLBENZYL)-2-THIOUREA
• CAS NO: 103854-74-6
• Molecular Formula: C₉H₁₂N₂S
• Molecular Weight: 180.27
• Mol File: 103854-74-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 120-122°C
• Boiling Point: 317.5 °C at 760 mmHg
• Flash Point: 145.8 °C
• Appearance: /
• Density: 1.155 g/cm³
• Vapor Pressure: 0.000384mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 1-(4-METHYLBENZYL)-2-THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHYLBENZYL)-2-THIOUREA(103854-74-6)
• EPA Substance Registry System: 1-(4-METHYLBENZYL)-2-THIOUREA(103854-74-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 103854-74-6(Hazardous Substances Data)

Usage

General Description

1-(4-Methylbenzyl)-2-thiourea is a chemical compound with the molecular formula C9H12N2S. It is a thiourea derivative, and its structure consists of a benzene ring with a methyl group and a thiourea group attached to it. 1-(4-METHYLBENZYL)-2-THIOUREA has potential applications in the field of medicine and pharmaceuticals, as it has been investigated for its antibacterial and antifungal properties. Additionally, it has been studied for its potential use as a corrosion inhibitor in metal surfaces. Its synthesis and properties make it a compound of interest for further research and potential practical applications in various industries.

InChI:InChI=1/C9H12N2S/c1-7-2-4-8(5-3-7)6-11-9(10)12/h2-5H,6H2,1H3,(H3,10,11,12)

Upstream product

• 1158621-31-8 N-((4-methylbenzyl)carbamothioyl)benzamide 
• 104-84-7 para-methylbenzylamine 
• 26177-45-7 4-methylbenzylamine hydrochloride 
• 3694-46-0 p-methylbenzyl isothiocyanate 

Downstream Products

• 93331-19-2 2-(4-methyl-benzylamino)-5-phenyl-thiazol-4-one 
• 91566-50-6 5-methyl-2-(4-methyl-benzylamino)-thiazol-4-one 
• 93329-89-6 5-(2-chloro-phenyl)-2-(4-methyl-benzylamino)-thiazol-4-one 
• 93329-90-9 5-(4-chloro-phenyl)-2-(4-methyl-benzylamino)-thiazol-4-one 
• 92648-21-0 5-butyl-2-(4-methyl-benzylamino)-thiazol-4-one 
• 92107-96-5 5-ethyl-2-(4-methyl-benzylamino)-thiazol-4-one 

Relevant articles and documents

COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA

The present invention provides aminohydantoin anti-malarial agents. In some embodiments, these agents have the property of functions of targeting malarial aspartic proteases while at the same time having low activity against human BACE. Methods of employing such agents are also provided.

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors

The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.