1038732-03-4Relevant articles and documents
Fluorescent Sensing of Guanine and Guanosine Monophosphate with Conjugated Receptors Incorporating Aniline and Naphthyridine Moieties
Lu, Shao-Hung,Phang, Riping,Fang, Jim-Min
, p. 1724 - 1727 (2016)
Ethyne-linked naphthyridine-aniline conjugated molecules are selective sensors of decylguanine in dichloromethane and guanosine monophosphate in water (Kass = 16 000 M-1). The 2-acetamido-1,8-naphthyridine moiety binds with guanine in a DAA-ADD triply hydrogen-bonded motif. The aniline moiety enhances an electron-donating effect, and the substituent is tuned to attain extra hydrogen bonds, π-π stacking, and electrostatic interactions. The proposed binding modes are supported by a Job plot, ESI-MS, 1H NMR, UV-vis, and fluorescence spectral analyses.
New entry to polycyclic fused indoles via gold(I)-catalyzed cascade reaction
Chiarucci, Michel,Matteucci, Elia,Cera, Gianpiero,Fabrizi, Giancarlo,Bandini, Marco
supporting information, p. 1776 - 1779 (2013/09/02)
The gold standard: A gold-catalyzed cascade reaction sequence for the preparation of polycyclic fused indole cores exploits the ready availability and chemical flexibility of propargylic alcohols. The desired tri- or tetracyclic compounds are obtained in good yields with water as the only stoichiometric by-product. Copyright
