1038827-63-2 Usage
General Description
6-Fluoroimidazo[1,2-a]pyridine-2-methanol is a chemical compound with the molecular formula C8H7FN2O. It is a fluoro-substituted imidazopyridine derivative, and it contains an imidazo[1,2-a]pyridine core with a fluorine atom and a hydroxyl group attached to it. 6-Fluoroimidazo[1,2-a]pyridine-2-methanol has potential applications in medicinal chemistry, particularly in the development of pharmaceutical drugs targeting specific biological pathways. Its unique structure and functional groups make it a valuable building block for the synthesis of novel drug candidates and research compounds. Additionally, it may also have applications in other fields such as materials science and organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1038827-63-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,8,8,2 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1038827-63:
(9*1)+(8*0)+(7*3)+(6*8)+(5*8)+(4*2)+(3*7)+(2*6)+(1*3)=162
162 % 10 = 2
So 1038827-63-2 is a valid CAS Registry Number.
1038827-63-2Relevant articles and documents
Discovery of imidazopyridine derivatives as highly potent respiratory syncytial virus fusion inhibitors
Feng, Song,Hong, Di,Wang, Baoxia,Zheng, Xiufang,Miao, Kun,Wang, Lisha,Yun, Hongying,Gao, Lu,Zhao, Shuhai,Shen, Hong C.
, p. 359 - 362 (2015)
A series of imidazolepyridine derivatives were designed and synthesized according to the established docking studies. The imidazopyridine derivatives were found to have good potency and physical-chemical properties. Several highly potent compounds such as 8ji, 8jl, and 8jm were identified with single nanomolar activities. The most potent compound 8jm showed an IC50 of 3 nM, lower microsome clearance and no CYP inhibition. The profile of 8jm appeared to be superior to BMS433771, and supported further optimization.
CHEMICAL COMPOUNDS 635 : PYRIDOPYRIMIDINEDIONES AS PDE4 INHIBITORS
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Page/Page column 38, (2008/12/07)
The present invention provides a compound of a formula (I): wherein the variables are defined herein; to a process for preparing such a compound; and to the use of such a compound in the treatment of a PDE 4 mediated disease state.
