103889-16-3Relevant academic research and scientific papers
ANTIARRHYTHMIC AGENTS
-
, (2008/06/13)
A pharmaceutical composition for treating cardiac arrhythmias or inhibiting ventricular tachycardias comprises an effective amount of a compound having the structural formula: STR1 or a pharmaceutically acceptable salt thereof; wherein at least one R 1 is H and the other R 1 is H, alkyl, halogen, alkoxy or alkylthio;R 2 is alkyl containing at least 2 carbon atoms, benzyl or aryl; R 3 is alkyl or aryl; andR a and R b taken together with the carbon and nitrogen atoms to which they are attached represent a heterocyclic group; together with a non-toxic pharmaceutically acceptable carrier. The compounds and compositions are useful in methods of treating cardiac arrhythmias and inhibiting ventricular tachycardias in mammalian subjects.In composition of matter aspect, this invention relates to certain novel 2-(2-iminoethylidene)benzimidazolines and neutral tautomers thereof.
