103890-69-3

Basic information

• Product Name: (E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester
• Synonyms: (E)-3-(2-FORMYIPHENYL)-2-PROPENOIC ACID 1,1-DIMETHYL ETHYL ESTER;(e)-3-(2-formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester;(E)-3-(2-Formylphenyl)-2-Prope;(E)-3-(2-FORMYLPHENYL)-2-PROPENOIC ACID 1,1-DIMETHYL ETHYL ESTER,80+%;(E)-tert-Butyl 3-(2-forMylphenyl)acrylate;(E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl este
• CAS NO: 103890-69-3
• Molecular Formula: C₁₄H₁₆O₃
• Molecular Weight: 232.28
• Mol File: 103890-69-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 355.64 °C at 760 mmHg
• Flash Point: 156.028 °C
• Appearance: /
• Density: 1.098g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: (E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester(103890-69-3)
• EPA Substance Registry System: (E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester(103890-69-3)

Safety Data

• Hazardous Substances Data: 103890-69-3(Hazardous Substances Data)

Usage

General Description

The chemical compound "(E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester" is an ester derivative of (E)-3-(2-formylphenyl)-2-propenoic acid. It is commonly used as a flavoring agent and fragrance ingredient in the cosmetic and personal care industry. (E)-3-(2-Formylphenyl)-2-propenoic acid 1,1-dimethyl ethyl ester has a fruity, green, and floral odor, making it suitable for use in various products such as perfumes, colognes, and other scented items. It is also used as a flavor additive in food products due to its aromatic and sweet taste. Additionally, it is utilized in the production of pharmaceuticals and as an intermediate in organic synthesis. However, it is important to handle this chemical with caution as it can be potentially hazardous if not used properly.

InChI:InChI=1/C14H16O3/c1-14(2,3)17-13(16)9-8-11-6-4-5-7-12(11)10-15/h4-10H,1-3H3/b9-8+

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 89-98-5 2-chloro-benzaldehyde 
• 5425-44-5 2-Phenyl-[1,3]dithiane 
• 6630-33-7 ortho-bromobenzaldehyde 
• 59159-39-6 (tert-butoxycarbonylmethyl)triphenylphosphonium bromide 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 86302-43-4 (tert-Butoxycarbonylmethylene)triphenylphosphorane 

Downstream Products

• 1229445-65-1 (E)-tert-butyl 3-(2-(2,2-dibromovinyl)phenyl)acrylate 
• 1256262-90-4 tert-butyl (E)-3-(2-((E)-3-oxobut-1-en-1-yl)phenyl)acrylate 

Relevant articles and documents

A facile, one-pot synthesis of lacidipine using in situ generation of wittig intermediates

An improved, one-pot process for the preparation of lacidipine (1) via an efficient in situ generation of Wittig intermediates is reported. Generation of ylide (4) by dehydrobromination of phosphonium salt (3) followed by in situ condensation of 4 with o-phthalaldehyde (5) to yield corresponding olefin (6) and its subsequent reaction with crotonate derivative (7) in the same pot furnished the drug substance 1 with an overall yield of about 51% over the reported yield of about 24% starting from the corresponding ylide. The present work overcomes the challenges associated with prior art processes such as chromatographic purifications, handling of unstable intermediates, and formation of byproducts as potential impurities. The interesting insights on the safety aspects of the process, drawn through calorimetric studies, rendered the successful implementation of the process at manufacturing facility.

A solvent- And catalyst-free tandem reaction: Synthesis, and photophysical and biological applications of isoindoloquinazolinones

An easy green synthetic approach for fused isoindoloquinazolinones has been developed under neat reaction (yields up to 91%) conditions. This new one-pot tandem methodology involves condensation of readily available anthranilamide with 3-(2-formylcycloalk

Synthesis of Oxatricyclooctanes via Photoinduced Intramolecular Oxa-[4+2] Cycloaddition of Substituted o-Divinylbenzenes

The photolysis of substituted o-divinylbenzenes promotes a one-step and metal-free conversion to oxatricycles at room temperature. Irradiation o-divinylbenzenes results in an pericyclic reaction to form cyclic o-quinodiemthane intermediates, which subsequently undergo intramolecular oxa-[4+2] cycloaddition to form oxacyclic derivatives.